75 results found
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Modeling transfer of vaginal microbiota from mother to infant in early life

    Martin Steen Mortensen, Morten Arendt Rasmussen ... Søren Johannes Sørensen
    Modeling weighted transfer ratios enable statistical analysis of maternal–infant transfer at a more general level and can indicate whether any transfer is persistent, transient, or originates from alternate sources.
    1. Ecology
    2. Microbiology and Infectious Disease

    Competition for fluctuating resources reproduces statistics of species abundance over time across wide-ranging microbiotas

    Po-Yi Ho, Benjamin H Good, Kerwyn Casey Huang
    A simple model provides an accessible framework to infer macroscopic parameters of effective resource competition from longitudinal studies of microbial communities.
    1. Computational and Systems Biology
    2. Medicine

    The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study

    Zachary Shaffer, Roberto Romero ... Nardhy Gomez-Lopez
    The vaginal immunoproteome in pregnancy is more predictive of spontaneous preterm birth (sPTB) than maternal characteristics alone, with sPTB cases showing heightened pro-inflammatory profiles accompanied by reduced levels of antimicrobial proteins/peptides.
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    Identification of fallopian tube microbiota and its association with ovarian cancer

    Bo Yu, Congzhou Liu ... David N Fredricks
    A prospective study of intraoperative swab collections from 187 patients identified a putative fallopian tube microbiota and a clear shift in ovarian cancer patients compared to non-cancer patients.
    1. Medicine

    Fungal–bacteria interactions provide shelter for bacteria in Caesarean section scar diverticulum

    Peigen Chen, Haicheng Chen ... Xing Yang
    Local abnormal fungi in Caesarean section scar diverticulum can affect the abundance of bacteria through specific metabolites, thereby destroying the stability of bacteria and the entire microbial community.
    1. Microbiology and Infectious Disease

    Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

    Soner Yildiz, João P Pereira Bonifacio Lopes ... Mirco Schmolke
    A respiratory tissue-associated commensal Lactobacillus strain confers colonization resistance to Streptococcus pneumoniae, when applied therapeutically in a post influenza virus super-infection model.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A phylogenetic transform enhances analysis of compositional microbiota data

    Justin D Silverman, Alex D Washburne ... Lawrence A David
    The PhILR transform uses an evolutionary model to overcome statistical challenges associated with microbiota surveys.
    1. Medicine

    The gut microbiota is a transmissible determinant of skeletal maturation

    Abdul Malik Tyagi, Trevor M Darby ... Roberto Pacifici
    The gut microbiota is a non-genomic, transmissible regulator of bone volume, structure, and turnover.
    1. Microbiology and Infectious Disease

    Ribonucleotide reductase, a novel drug target for gonorrhea

    Jana Narasimhan, Suzanne Letinski ... Arthur Branstrom
    Novel small molecule inhibitors act against Neisseria including multi-drug resistant isolates by uniquely targeting RNR thereby enabling single pathogen therapy whilst sparing the microbiome.
    1. Cell Biology

    Microbiome: Balancing microbial composition through diet

    L Catalina Acuff, Karen Guillemin
    A reciprocal interaction between gut bacteria and gut cells affects protein absorption in the host.
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