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Episode 49: August 2018
In this episode, we hear about the RNA world, bovine TB, lung fibrosis, and why rock pigeons have different wing patterns.
Episode 56: April 2019
In this episode, we hear about multipartite viruses, brain maps of people without hands, measles vaccinations, reproducible science, and how to spot premature babies.
The Natural History of Model Organisms
Edited by Ian Baldwin et al.
Essays on the wild lives of model organisms, from
to the zebrafish.
Episode 69: September 2020
In this episode, we hear about prostate cancer, cultural diversity in bonobos, blood fat imbalances in Latin America and the Caribbean, insect behaviour, and how astrocytes can form new neurons.
Episode 64: February 2020
In this episode we hear about genetic privacy, plants with three parents, using cannabis to treat endometriosis, a new type of hearing test and how we can enjoy a cuddle.
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
Sumiko Takao et al.
Definition of leukemia gene expression mechanisms reveals general principles of cancer gene control and offers a pharmacologic strategy for its therapeutic reprogramming.
Physics of Living Systems
Epithelial colonies in vitro elongate through collective effects
Jordi Comelles et al.
Spontaneous elongation of epithelial colonies is related to the orientation of the mean nematic cell elongation field, as shown and tested with experiments and theory.
Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division
Jin Rong Ow et al.
Loss of hepatic
leads to oxidative stress, increased fatty acids in blood, and hyperinsulinemia, which resulted in insulin resistance and hepatic steatosis, similar as in diabetes.
TrpML-mediated astrocyte microdomain Ca
transients regulate astrocyte–tracheal interactions
Zhiguo Ma, Marc R Freeman
Astrocyte microdomain calcium transients are mediated by TrpML, stimulated by ROS and tyramine, and mediate astrocyte–tracheal interactions in CNS gas exchange.
Chromosomes and Gene Expression
SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis
Alisa Atkins et al.
The structural maintenance of chromosomes complex, SMC5/6, is crucial for brain development and function as it ensures proficient DNA replication in neural progenitor cells prior to chromosome segregation.
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