71 results found
    1. Microbiology and Infectious Disease

    A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface

    Marcin Grabowicz et al.
    A single mutation in Escherichia coli connects two essential cell envelope assembly pathways and confers vancomycin resistance by displaying molecular decoys at the cell surface.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement

    Aleksandra Zielińska et al.
    Correct cell wall synthesis in bacteria depends on flotillin-mediated membrane fluidity.
    1. Developmental Biology
    2. Plant Biology

    Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

    Anne Pfeiffer et al.
    TOR kinase guides the transition of plant stem cells from the dormant embryonic state to the active adult state by integrating light and metabolic signals.
    1. Microbiology and Infectious Disease

    Lipoprotein DolP supports proper folding of BamA in the bacterial outer membrane promoting fitness upon envelope stress

    David Ranava et al.
    The envelope stress factor DolP associates with the outer membrane protein assembly machinery and supports proper folding and functioning of BamA contributing to preserve envelope integrity.
    1. Evolutionary Biology

    An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

    Valerie J Morley et al.
    Cholestyramine, an FDA-approved bile acid sequestrant, can be repurposed to inactivate the antibiotic daptomycin in the gut, which prevents the emergence of transmissible antibiotic resistance in gastrointestinal Enterococcus faecium populations.
    1. Microbiology and Infectious Disease

    The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane

    Cassandra Kamischke et al.
    An Acinetobacter baumannii ABC transporter likely facilitates transport of glycerophospholipids from the inner to the outer membrane.
    1. Microbiology and Infectious Disease

    Gut microbiota density influences host physiology and is shaped by host and microbial factors

    Eduardo J Contijoch et al.
    The density of the gut microbiota influences the host immune system and adiposity, and can be therapeutically manipulated.
    1. Microbiology and Infectious Disease

    Molecular coordination of Staphylococcus aureus cell division

    Victoria A Lund et al.
    Morphological constraints dictate division mode in the human pathogen Staphylococcus aureus.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Limitations to photosynthesis by proton motive force-induced photosystem II photodamage

    Geoffry A Davis et al.
    Storage of solar energy in the thylakoid electrical field by photosynthesis in vivo can substantially destabilize charge-separated states in photosystem II, leading to singlet oxygen production and photodamage, contributing to loss of productivity, especially under fluctuating light experienced in the field.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

    Liana F Lareau et al.
    The size of the mRNA fragment protected by a ribosome depends on the ribosome's conformation, which enables studies of the distinct steps of decoding and translocation at single-codon resolution.

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