2,564 results found
    1. Cell Biology
    2. Physics of Living Systems

    The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy

    Akanksha Thawani et al.
    Four αβ-tubulin dimers associate laterally on γ-TuRC to define the rate-limiting transition state for microtubule nucleation.
    1. Cell Biology

    A microscopy-based kinetic analysis of yeast vacuolar protein sorting

    Jason C Casler, Benjamin S Glick
    In yeast, a fluorescent vacuolar cargo departs from Golgi cisternae early in the TGN stage of maturation, and traffic from prevacuolar endosomes to the vacuole apparently involves a kiss-and-run mechanism.
    1. Genetics and Genomics

    Alternative polyadenylation mediates genetic regulation of gene expression

    Briana E Mittleman et al.
    Genetic variation can impact multiple levels of gene regulation and disease through alternative polyadenylation.
    1. Neuroscience

    Long-term implicit memory for sequential auditory patterns in humans

    Roberta Bianco et al.
    Human listeners rapidly form robust, long lasting (up to 7 weeks) memories of rarely encountered, featureless sound sequences presented among many similar stimuli.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival

    Huy Q Ta et al.
    CHK2 directly binds the AR to mediate transient suppression of AR activity and thus loss of CHK2 function in prostate cancer increases AR activity, DNA damage response and radiation resistance.
    1. Neuroscience
    2. Physics of Living Systems

    Tuning of feedforward control enables stable muscle force-length dynamics after loss of autogenic proprioceptive feedback

    Joanne C Gordon et al.
    Running guinea fowl maintain stable running after loss of the stretch reflex in a major ankle extensor muscle, by increasing feedforward muscle activation to maintain ankle stiffness and work output.
    1. Neuroscience

    Vestigial auriculomotor activity indicates the direction of auditory attention in humans

    Daniel J Strauss et al.
    Recordings of ear muscles in humans show that ears attempt to pivot in the direction that requires attention.
    1. Ecology
    2. Physics of Living Systems

    Ant collective cognition allows for efficient navigation through disordered environments

    Aviram Gelblum et al.
    When real ants confront the classical 'Ant-in-a-labyrinth' physics problem where a random walker traverses a percolated environment, they employ active extended sensing and collective cognition to outperform passive physical solutions.
    1. Neuroscience

    Automated task training and longitudinal monitoring of mouse mesoscale cortical circuits using home cages

    Timothy H Murphy et al.
    A new methodology and protocol use automated brain imaging and task training technology to probe links between behavior and mouse cortical circuits.
    1. Neuroscience

    Temperature compensation in a small rhythmic circuit

    Leandro M Alonso, Eve Marder
    Computational models demonstrate that circuit resilience to temperature perturbations are associated with smooth transitions between cellular mechanisms as the contributions of different currents are altered while activity is maintained.

Refine your results by:

Type
Research categories