The in vivo transcriptomic fingerprint encoding defective decidualization comprises 120 genes associated with an imbalance hormonal signaling in the decidual endometria of women who developed severe preeclampsia.

Discrepancies between functional responses measured with electrophysiology and calcium imaging can be largely reconciled by considering the spike-to-calcium transfer function, neuronal sampling bias, and cluster merging artifacts during spike sorting.

Vigorous endurance training results in prolongation of cardiac repolarization and increased repolarization instability, mild ventricular fibrosis associated with decrease of the transient outward potassium current, and enhanced arrhythmia susceptibility in canine model.

Leaf position, shape and orientation are pre-patterned by cell type boundaries in the shoot meristem.

The Wtf4 antidote protein assembles with the Wtf4 poison protein and promotes the transportation of the assembled proteins to the vacuole for sequestration or destruction.

Orthologous proteins that continuously maintain the same molecular function do not usually diverge beyond a certain level of sequence and structural similarity.

Exceptionally long-lived macromolecules in mammalian ovaries and oocytes serve as pillars for lifelong reproductive health span.

A new molecular mechanism involving microRNA, which controls synaptic transmission in a specialized type of inhibitory interneurons in the hippocampus and short-term memory in mice, was identified.

The amyloid polymorph selection that occurs during α-synuclein aggregation is dictated by environmental conditions, in particular pH, with the largest variety of structures being observed near neutral pH.

Plasticity arising from autocatalytic receptor activation coexists with robustness in ligand responsiveness only by differential endosomal sorting of spontaneous and ligand-activated EGFR as distinct molecular states.