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Transcriptome analysis reveals an alternative splicing program induced in the arterial endothelium under low-flow inflammatory conditions by platelet and macrophage recruitment and dependent upon the RNA-binding splice factor Rbfox2.

Novel and common angiogenic mechanisms crucial for fenestrated brain capillary formation have been identified.

Direct reprogramming of smooth muscle cells from HGPS patients revealed that BMP4 is a key contributor of vascular degeneration and might represent a new therapeutic target.

Fibrinogen, a key protein involved in blood coagulation, contains a disordered and previously poorly characterised region called αC that plays a critical role in fibrin fibre growth and clot stability.

Cross-species multiomics network modeling revealed tissue-specific regulatory genes, pathways, and networks shared between mouse and human or unique to each species for atherosclerosis and coronary artery disease.

Genome-wide integration of transcriptome, accessible chromatin, and DNA methylome data from vascular endothelial cells lays the foundation for understanding the gene regulatory circuits that generate organ-specific vascular specialization.

The eye produces a protein that inhibits the growth of blood vessels in the deep retina, which includes the photoreceptor layer, and disruption of this process can lead to blindness.

Radial plant growth produces large parts of terrestrial biomass and can be computationally simulated with the help of an instructive framework of intercellular communication loops.

While semantic symptoms in fronto-temporal dementia patients were mainly dependent on short-range white-matter fibre disruption, long-range white-matter fibres damage was the major contributor to executive dysfunction, highlighting the importance of controlling for risk factors associated with deep white-matter disease.

Genetic studies reveal a role for Yap1 in lymphatic endothelial progenitor cell sprouting and proliferation during early zebrafish lymphatic vascular development.