Integrin and actin associated proteins are resolved into four layers within myofibril attachments, an architecture requiring balanced positive and negative regulation of integrin adhesion with integrated mechanotransduction and actin pathways.
Cerebellar functional regions follow a gradual organization, which progresses from primary (motor) to transmodal (Default Mode Network) regions, and a secondary axis extends from task-unfocused to task-focused processing.
Intracranial recordings of human brain activity during awakening from general anesthesia exhibit a brief brain state not seen during loss of consciousness, in which stimuli elicit large electrophysiological responses that resemble those seen in sleep.
Immunolabelling and morphological assessment, complemented by complete transcriptomic analysis, demonstrates that supporting cells can be induced to convert towards a hair cell-like phenotype in human vestibular sensory epithelia.
A newly described isolate of the behavior-manipulating fly pathogen Entomophthora muscae that naturally infects fruit flies can be cultured in the lab, enabling molecular investigation of how microbes induce behavior changes in animal hosts.