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    1. Cancer Biology
    2. Cell Biology

    Opto-magnetic capture of individual cells based on visual phenotypes

    Loïc Binan et al.
    Single cells from a large heterogeneous population can be identified, isolated and clonally expanded using commonly available microscopy equipment and simple reagents, based solely on visual characteristics.
    1. Neuroscience

    Parallel visual circuitry in a basal chordate

    Matthew J Kourakis et al.
    The ascidian Ciona integrates visual information from two photoreceptor types through convergent excitatory and disinhibitory circuits, thereby evoking swim behaviors.
    1. Developmental Biology

    GIPC proteins negatively modulate Plexind1 signaling during vascular development

    Jorge Carretero-Ortega et al.
    Zebrafish mutants and human endothelial cell experiments reveal that GIPC family endocytic adaptors bind to the Semaphorin receptor PLEXIND1, a critical regulator of vascular development, to negatively modulate its signaling.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle

    Qingnian Goh et al.
    Fusion of muscle progenitors drives continuous myonuclear accretion during exercise and impacts various adaptations in skeletal muscle including response to injury and hypertrophy.
    1. Cell Biology
    2. Neuroscience

    Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

    Guiping Wang et al.
    Neurotrophin deprivation leads to rapid caspase-independent disassembly of the actin-spectrin-based membrane skeleton and spectrin-dependent retrograde signaling in axon degeneration.
    1. Cell Biology

    Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

    Pierre Cunin et al.
    In a novel cell-in-cell interaction termed emperipolesis, neutrophils routinely transit through the cytoplasm of bone marrow megakaryocytes to pass surface membrane to newly-generated hybrid platelets.
    1. Neuroscience

    Image content is more important than Bouma’s Law for scene metamers

    Thomas SA Wallis et al.
    Peripheral appearance models emphasising pooling processes that depend on retinal eccentricity will instead need to explore input-dependent grouping and segmentation.
    1. Neuroscience

    Oscillatory hyperactivity and hyperconnectivity in young APOE-ɛ4 carriers and hypoconnectivity in Alzheimer’s disease

    Loes Koelewijn et al.
    Electrophysiology pinpoints brain function abnormalities in young people genetically at risk of developing Alzheimer's disease much later in life, supporting theories of initial hyperconnectivity driving eventual profound disconnection.
    1. Neuroscience

    The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression

    Alexandra Fletcher-Jones et al.
    An intracellular H9 motif facilitates the highly localised axonal surface expression of CB1R.
    1. Neuroscience

    Anterior insular cortex plays a critical role in interoceptive attention

    Xingchao Wang et al.
    Anterior insular cortex activity predicts how well we attend to our bodily signals, while lesions to this brain region disrupt this ability.