1,149 results found
    1. Microbiology and Infectious Disease

    Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer

    Yang Li et al.
    L. interrogans utilizes endocytic recycling and vesicular transport systems for transcytosis across endothelial or epithelial barrier in blood vessels or renal tubules, which contributes to spreading and transmission of leptospirosis.
    1. Cell Biology
    2. Human Biology and Medicine

    Myogenic vasoconstriction requires G12/G13 and LARG to maintain local and systemic vascular resistance

    Ramesh Chennupati et al.
    Genetic mouse models identify a critical mechanism of myogenic vasoconstriction and reveal the in vivo function of myogenic autoregulation in protecting from organ overperfusion and in maintaining vascular resistance.
    1. Cell Biology
    2. Human Biology and Medicine

    Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy

    Louise A Moyle et al.
    Rescue of DUX4-induced muscle pathology by the RET inhibitor Sunitinib reveals the therapeutic potential for treatment of Facioscapulohumeral muscular dystrophy using tyrosine kinase inhibitors.
    1. Stem Cells and Regenerative Medicine

    Skin vasculature and hair follicle cross-talking associated with stem cell activation and tissue homeostasis

    Kefei Nina Li et al.
    Hair follicle epithelium and skin vasculature remodeling are coordinated during quiescence, and their cross-talking is associated with the timing of stem cell activation.
    1. Stem Cells and Regenerative Medicine

    Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1

    Bo O Zhou et al.
    Normal hematopoietic stem and progenitor cells slow the regeneration of their niche after injury to minimize leakage from the niche vasculature.
    1. Cancer Biology
    2. Immunology and Inflammation

    Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes

    Amy W Ku et al.
    Tumor-induced myeloid-derived suppressor cells exert systemic suppression of adaptive immunity by limiting L-selectin-directed trafficking of T cells at vascular checkpoints in lymph nodes.
    1. Developmental Biology
    2. Neuroscience

    Radial glia regulate vascular patterning around the developing spinal cord

    Ryota L Matsuoka et al.
    Identification of a novel role for central nervous system-resident progenitors in the patterning of the vascular network around the developing spinal cord.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Piezo Ion Channels: Portraits of a pressure sensor

    Alexander T Chesler, Marcin Szczot
    Near atomic-resolution structures have provided insights into the mechanisms by which the Piezo1 ion channel senses and responds to mechanical stimuli.
    Insight
    Available as:
    • HTML
    • PDF

Refine your results by:

Type
Research categories