85 results found
    1. Neuroscience

    A ventral hippocampal-lateral septum pathway regulates social novelty preference

    Maha Rashid, Sarah Thomas ... Malavika Murugan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

    Igor Kondrychyn, Haymar Wint ... Li-Kun Phng
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Connectomics of the Octopus vulgaris vertical lobe provides insight into conserved and novel principles of a memory acquisition network

    Flavie Bidel, Yaron Meirovitch ... Binyamin Hochner
    Connectomics of the octopus 'fan-out fan-in’ learning network reveals that the intermediate layer uses approximately 22×106 excitatory interneurons, each can store a single sensory input, while approximately 400×103 integrating inhibitory interneurons adjust the network output level.
    1. Cell Biology

    A bioactive peptide amidating enzyme is required for ciliogenesis

    Dhivya Kumar, Daniela Strenkert ... Betty A Eipper
    Analysis of Chlamydomonas, planaria and mice reveals a novel and unanticipated role for a peptide amidating enzyme in primary and motile ciliary assembly through effects on post-Golgi trafficking.
    1. Computational and Systems Biology
    2. Neuroscience

    Daily electrical activity in the master circadian clock of a diurnal mammal

    Beatriz Bano-Otalora, Matthew J Moye ... Mino DC Belle
    Circadian control of neuronal excitability in the master circadian clock of a diurnal mammal as revealed by whole-cell recording and mathematical modeling.
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse

    Yuanyuan Li, Wenyan Xu ... Zhaoxia Sun
    Genetic and chemical genetic analysis pinpoint defective epithelial cells as the driver for NPHP like phenotypes in Invs mutants, demonstrate genetic interaction between Invs and Ift88 and identify the HDAC inhibitor valproic acid as a suppressor for Invs mutant phenotypes.
    1. Neuroscience

    Seasonal plasticity in GABAA signaling is necessary for restoring phase synchrony in the master circadian clock network

    Kayla E Rohr, Harshida Pancholi ... Jennifer Evans
    A seasonal switch to excitatory GABAA signaling dictates how daily clock neurons interact to encode environmental change.
    1. Neuroscience

    PVN-mPFC OT projections modulate pup-directed pup care or attacking in virgin mandarin voles

    Lu Li, Yin Li ... Fadao Tai
    Activation of oxytocin (OT) neurons in the paraventricular nucleus or their projections to medial prefrontal cortex or periphery OT administration facilitated pup caring and inhibited infanticide, while inhibitions of these neurons and projections promoted infanticide.
    1. Neuroscience

    Perception of social interaction compresses subjective duration in an oxytocin-dependent manner

    Rui Liu, Xiangyong Yuan ... Wen Zhou
    The subjective time of social interactions reflects one's autistic-like tendency and is critically mediated by oxytocin, indicating that time perception is ingrained with personality traits, which likely have neuroendocrine origins as per previous research.

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