72 results found
    1. Ecology
    2. Evolutionary Biology

    Dynamics of venom composition across a complex life cycle

    Yaara Y Columbus-Shenkar et al.
    Different developmental stages of a venomous animal (e.g. Nematostella vectensis) with a complex life cycle produce vastly different venoms that can serve in different antagonistic interactions with other species.
    1. Cell Biology
    2. Immunology and Inflammation

    Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism

    Leonie Zeitler et al.
    IL4i1 is an amino acid oxidase expressed in the mammalian immune system and snake venoms, which control diametrically opposite cell protection versus cell death pathways, respectively.
    1. Ecology

    The golden mimicry complex uses a wide spectrum of defence to deter a community of predators

    Stano Pekár et al.
    A mimetic complex composed of at least 140 species of ants, wasps, spiders, true bugs and treehoppers, all with conspicuous golden bodies, has been discovered.
    1. Structural Biology and Molecular Biophysics

    Structure and analysis of nanobody binding to the human ASIC1a ion channel

    Yangyu Wu et al.
    Development of specific and high-affinity nanobodies to probe the structure of human acid sensing ion channel-1a and as binding modifiers of the toxins PcTx and MitTx1.
    1. Evolutionary Biology

    Constitutive activation of cellular immunity underlies the evolution of resistance to infection in Drosophila

    Alexandre B Leitão et al.
    Single-cell transcriptomics of immune cells demonstrates that populations evolve inducible defences when infection rates are low and constitutive defences when infection is common.
    1. Genetics and Genomics

    Amino acid synthesis loss in parasitoid wasps and other hymenopterans

    Xinhai Ye et al.
    The synthesis capability of some amino acids is lost during the insect evolution, and hymenopteran parasitoids can make up for these deficiencies by altering free amino acid concentrations in host.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    A molecular filter for the cnidarian stinging response

    Keiko Weir et al.
    Cnidarian stinging cells use a specialized voltage-gated calcium channel to integrate distinct sensory signals and selectively trigger a predatory response.
    1. Neuroscience

    Voltage-gated Na+ currents in human dorsal root ganglion neurons

    Xiulin Zhang et al.
    Human sensory neurons may not only bridge a critical gap between drug discovery and clinical trials, but force a re-evaluation of basic assumptions about the mechanisms controlling primary afferent excitability.
    1. Biochemistry and Chemical Biology

    Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

    Peter Ahorukomeye et al.
    The unique modus operandi of cone snail venom insulins provides new insight into insulin receptor activation and informs on the design of insulin analogs for the treatment of diabetes.
    1. Ecology
    2. Genetics and Genomics

    Education and Outreach: March Mammal Madness and the power of narrative in science outreach

    Katie Hinde et al.
    Hypothetical battles between animals can be used to interest the general public in biology.

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