973 results found
    1. Microbiology and Infectious Disease

    Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer

    Yang Li et al.
    L. interrogans utilizes endocytic recycling and vesicular transport systems for transcytosis across endothelial or epithelial barrier in blood vessels or renal tubules, which contributes to spreading and transmission of leptospirosis.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

    Heidi Hehnly et al.
    A protein kinase complex that is important for cell division is lost in testicular seminoma, which is a common cancer in men.
    1. Neuroscience

    Transformation of spatiotemporal dynamics in the macaque vestibular system from otolith afferents to cortex

    Jean Laurens et al.
    The spatial and dynamic properties of self-motion signals are acquired at the first stage of otolith signal transformation, which is in the brainstem and cerebellum, and conserved across brainstem, cerebellar and cortical areas.
    1. Physics of Living Systems

    A minimal self-organisation model of the Golgi apparatus

    Quentin Vagne et al.
    An unbiased model for the self-organisation of the Golgi apparatus displays either anterograde vesicular transport or cisternal maturation depending on ratios of budding, fusion and biochemical conversion rates.
    1. Neuroscience

    A unified internal model theory to resolve the paradox of active versus passive self-motion sensation

    Jean Laurens, Dora E Angelaki
    Central vestibular regions in the brainstem and cerebellum perform dynamic Bayesian inference to combine motor commands and sensory signals into an optimal estimate of self-motion.
    1. Evolutionary Biology

    The evolution of the vestibular apparatus in apes and humans

    Alessandro Urciuoli et al.
    The morphology of the inner ear distinguishes major anthropoid clades and enables the proposal of various shared-derived features for apes as a whole, lesser apes, and great apes and humans.
    1. Neuroscience

    A primal role for the vestibular sense in the development of coordinated locomotion

    David E Ehrlich, David Schoppik
    Zebrafish use their sense of gravity and their cerebellum to coordinate the fin and body movements that, as they develop, allow them to better maintain balance as they climb.
    1. Neuroscience

    Down regulation of vestibular balance stabilizing mechanisms to enable transition between motor states

    Romain Tisserand et al.
    Down regulation of the gain from the vestibular sensory sources prior to the initiation of movement is a motor control solution to overcome the reflex-stabilizing mechanisms to enable motion from a postural orientation.
    1. Cell Biology

    ATP activation of peritubular cells drives testicular sperm transport

    David Fleck et al.
    Purinergic signaling controls mammalian sperm transport.
    1. Developmental Biology
    2. Neuroscience

    Conserved and divergent development of brainstem vestibular and auditory nuclei

    Marcela Lipovsek, Richard JT Wingate
    The development of brainstem auditory nuclei echoes the divergent evolutionary history of amniote auditory systems.

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