Browse the search results

A new study in monkeys suggests that treating HIV infection early with antiretroviral therapy reduces the number of latent viruses, but has little impact on viral reactivation when treatment stops.

Cellular and chemogenetic approaches identify a novel mode of chemotransduction involving regulation of basal breathing by CO₂/H+-dependent disinhibition.

A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.

Diverse histories of viral exposure, for example in individuals of different age, makes viral evolution less predictable with features of adaptive and neutral evolution.

Using a combination of all-atom molecular simulation and continuum membrane mechanics, M2 channels from influenza are shown to be stabilized in negative Gaussian curvature regions, such as the neck of budding viral particles, only in C2-symmetric conformations.

Respiratory alkalosis recruits the midline thalamus to provoke absence seizures.

Super-resolution microscopy reveals, at nanometric-scale, the highly organized protein structure of viroplasms, the viral factories used by rotavirus to replicate its genome and assemble new viral particles.

Glutamatergic–cholinergic neurons in the postinspiratory complex are critical for swallow motor patterning and the coordination of swallow and breathing, which is disrupted by chronic intermittent hypoxia, a condition seen in many disorders associated with dysphagia and aspiration pneumonia.

Transient DNA interactions by DNA-binding proteins are utilized by herpes simple virus as an alternative route to generate membraneless compartments in the nucleus without invoking phase separation.

Phylogenetic evidence suggests that the majority of HIV infections occurring in the UNAIDS Fast-track city Amsterdam continue to have an Amsterdam resident as source, indicating that the majority of HIV infections in Amsterdam could be prevented through city-level interventions.