Cue cells in the medial entorhinal cortex encode visual cues during virtual navigation, supporting the hypothesis that the brain represents visual cue information to error-correct grid cell firing during path-integration.
A mouse virtual reality system is presented which allows normal spatial behavior and place, grid and head-direction cell firing patterns in 2-D arenas, and is compatible with electrophysiology and multi-photon imaging.
Functional brain imaging of subjects while travelling through an alien virtual world reveals how brain regions encode novel environments from scratch thus enabling navigation.
Mnemonic representations in the human anterior-lateral entorhinal cortex change through learning to reflect an experienced temporal event structure and holistic temporal maps relate to memory recall.
Inhibitory interneuron activity is dynamically modulated in new environments while individual interneurons show consistent levels of activity modulation across multiple environments, suggesting functional specialization of inhibitory subnetworks.
Light-seeking strategies in Zebrafish larvae are dissected using a virtual-reality assay, and these data are used to establish minimal stochastic and neural-circuits models that quantitatively capture this behavior.
A control system model of cerebellar patients' movements provides insight into the cerebellum's role in reaching and informs a virtual reality intervention to improve patient reaches.