A mouse virtual reality system is presented which allows normal spatial behavior and place, grid and head-direction cell firing patterns in 2-D arenas, and is compatible with electrophysiology and multi-photon imaging.
Functional brain imaging of subjects while travelling through an alien virtual world reveals how brain regions encode novel environments from scratch thus enabling navigation.
Mnemonic representations in the human anterior-lateral entorhinal cortex change through learning to reflect an experienced temporal event structure and holistic temporal maps relate to memory recall.
Inhibitory interneuron activity is dynamically modulated in new environments while individual interneurons show consistent levels of activity modulation across multiple environments, suggesting functional specialization of inhibitory subnetworks.
Staff from the Mayo Clinic in the US and the Karolinska Institute in Sweden describe a joint transatlantic course intended to broaden the horizons of the next generation of researchers in the field of regenerative medicine.