189 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Reconstitution of bacterial autotransporter assembly using purified components

    Giselle Roman-Hernandez et al.
    A complex that catalyzes the membrane integration of β barrel proteins and a molecular chaperone promote the complete assembly of a bacterial virulence factor in vitro.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Rift Valley fever phlebovirus NSs protein core domain structure suggests molecular basis for nuclear filaments

    Michal Barski et al.
    Insight into the molecular assembly of a protein with a central role in infections paves the way to understanding how Rift Valley fever virus causes disease.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    The plant-specific transcription factors CBP60g and SARD1 are targeted by a Verticillium secretory protein VdSCP41 to modulate immunity

    Jun Qin et al.
    Genetic and biochemical analyses reveal a virulence mechanism employed by V. dahliae that involves inhibition of the transcription factor activity of CBP60g and SARD1.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin

    Katharina van Pee et al.
    The near-atomic cryoEM pore complex structure of pneumolysin, the main virulence factor of Streptococcus pneumoniae, shows how the individual domains rearrange during the pore formation.
  1. Living Science: Owning your mistakes

    Eve Marder
    Most scientists admit to their errors but, as Eve Marder explains, the scientific community as a whole needs to rethink the way it recognizes achievement.
    1. Microbiology and Infectious Disease

    Point of View: What next for gain-of-function research in Europe?

    Robin Fears, Volker ter Meulen
    A EASAC working group on gain-of-function research has emphasised the importance of ensuring that the necessary safeguards and policies are in place.
    1. Microbiology and Infectious Disease

    Phage Predation: Killing the killers

    Marianne De Paepe, Marie-Agnès Petit
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    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Rab GTPases: Mutant enzymes challenge all assumptions

    Ryan M Nottingham, Suzanne R Pfeffer
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