1,661 results found
    1. Biochemistry and Chemical Biology

    Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site

    Vladimir Khayenko, Cihan Makbul ... Hans M Maric
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

    Man Zhu, Meng Ma ... Jing Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

    Yingying Chen, Jeong Han Lee ... Ebenezer N Yamoah
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles

    Xu Zheng, Shi Yu ... Guangxun Meng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant

    Patsy R Tomlinson, Rachel G Knox ... Robert K Semple
    PIK3R1 mutations that cause immunodeficiency through PI3-kinase hyperactivation also cause SHORT syndrome, due to PI3-kinase hypofunction, attributable to PI3-kinase destabilisation and outcompetition by mutant PIK3R1.
    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia

    Maria Ardaya, Marie-Catherine Tiveron ... Fabio Cavaliere
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control

    Mykola Roiuk, Marilena Neff, Aurelio A Teleman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective

    Douwe Schulte, Marta Šiborová ... Joost Snijder
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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