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    1. Microbiology and Infectious Disease

    Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms

    Mie Suzuki Okutani, Shinya Okamura ... Hirotaka Ebina
    The novel live-attenuated SARS-CoV-2 nasal vaccine candidate is highly safe, induces robust cellular and mucosal immunity, and generates long-lasting neutralizing antibody titers.
    1. Computational and Systems Biology

    Discovering Root Causal Genes with High Throughput Perturbations

    Eric V Strobl, Eric R Gamazon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    A-to-I RNA editing of CYP18A1 mediates transgenerational wing dimorphism in aphids

    Bin Zhu, Rui Wei ... Pei Liang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Plant Biology

    Systems genomics of salinity stress response in rice

    Sonal Gupta, Simon C Groen ... Michael D Purugganan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Cancer Biology

    Intrinsic bioenergetic adaptations compensate for reduced mitochondrial content in HER2-driven mammary tumors

    Sara M Frangos, Henver S Brunetta ... Graham P Holloway
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Microbiology and Infectious Disease

    HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest

    Dhaval Ghone, Edward L Evans ... Aussie Suzuki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR

    Yan Zhang, Jingwan Han ... Zhihu Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Medicine

    Sperm fertility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA

    Charline Vilpreux, Guillaume Martinez ... Jessica Escoffier
    Revised
    Reviewed Preprint v2
    Updated
    • Inadequate
    1. Microbiology and Infectious Disease

    Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

    Xin Ma, Meng Li ... Xinyan Han
    FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

    Joseph A Bisson, Miriam Gordillo ... Todd Evans
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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