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Specific deletion of Cav3.2 channels in anterior pretectal neurons reduced mechanical and cold allodynia, pointing to Cav3.2 channels as prime targets to develop innovative analgesic pharmacology that will not only act at the peripheral level but also in central structures.

Three-dimensional imaging and automated, brain-wide cell counting yield new insight into the diversity of neurons that connect the brain to the spinal cord and their different sensitivity to spinal cord damage.

Neural and network activity within a pontine-cortical micturition circuit are finely coordinated with urodynamics to assure appropriate voiding behaviors.

Machine learning analyses reveal that the observation of acute pain inflictions and facial expressions of pain evoke shared pain-specific neural representations.

Regulatory T cells produce analgesic opioid peptides that limit heat sensitivity in mice, revealing a novel pain regulation mechanism independent of inflammation control.

The neural circuit underlying defecation behavior in Drosophila larvae has been identified and characterized.

Gut-innervating sensory neurons detect large food volumes and inhibit feeding in Drosophila through the mechanically gated ion channel Piezo.

A guide summarizing the diversity of cell types in the parabrachial nucleus.

The process of cytokinesis can allow cell lineages to intermix in mammalian epithelia, and cellular aspect ratio is a critical modulator of this behavior.