Cortex dynamically regulates the flow of sensory information by suppressing responses of non-relevant stimuli through mechanisms of adaptation, while boosting sensory responses that are behaviorally important.
A spatially-tuned normalization model accounts for neuronal responses to attended or unattended stimuli that are presented inside the classical receptive field or the surround, and explains various other observations.
Under conditions where the force of HIV infection per cell is high, partial attenuation of infection with inhibitors can increase the number of live infected cells and may paradoxically be beneficial for viral spread.
Primate amygdala neurons provide a coordinated representation of space and motivational significance whereby amygdala responses to visual stimuli predicting either rewards or aversive stimuli could influence spatial attention in a similar manner.
Analysis of epidemiological data reveals that viral loads in newly HIV-1 infected individuals in Uganda have declined for two decades, and evolutionary modelling shows that attenuation of the virus explains this decline.