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    1. Ecology

    Plant-associated CO2 mediates long-distance host location and foraging behaviour of a root herbivore

    Carla CM Arce, Vanitha Theepan ... Ricardo AR Machado
    The larvae of the western corn rootworm use root-emitted CO2 to successfully locate the most suitable host plant.
    1. Neuroscience

    Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons

    Sahana Sitaraman, Gnaneshwar Yadav ... Vatsala Thirumalai
    A protein that is a building block of intercellular bridges between neurons promotes their ability to grow dendrites and make synapses.
    1. Immunology and Inflammation

    Distinct T-cell receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

    Jasmine Rowell, Ching-In Lau ... Tessa Crompton
    The foetal thymic T-cell receptor (TCR) repertoire is distinct from adult, and it is less governed by MHC-restriction, more closely encoded by genomic sequence with distinct gene-segment usage including 3’TRAV to 5’TRAJ.
    1. Neuroscience

    Vocal development in a Waddington landscape

    Yayoi Teramoto, Daniel Y Takahashi ... Asif A Ghazanfar
    An integrated landscape framework shows how the coordinated changes in vocal apparatus, muscles, nervous system, and social interaction together influence the trajectory of vocal development.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure

    KM Rifat Faysal, James C Walsh ... Till Böcking
    The anti-HIV drug lenacapavir breaks the HIV capsid by stabilising regions of low curvature at the expense of maintaining a closed shell, leading to loss of viral DNA synthesis and inhibition of infection.
    1. Neuroscience

    Estimating and interpreting nonlinear receptive field of sensory neural responses with deep neural network models

    Menoua Keshishian, Hassan Akbari ... Nima Mesgarani
    A comprehensive, data-driven and interpretable nonlinear computational modeling framework based on deep neural networks uncovers different nonlinear transformations of speech signal in the human auditory cortex.
    1. Cell Biology
    2. Developmental Biology

    TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

    Xiaochen Fan, V Pragathi Masamsetti ... Patrick PL Tam
    Network propagation connects TWIST1 with epigenetic regulators CHD7, CHD8, and WHSC1, which collectively promote the bias toward neural crest while suppressing neural stem cell programmes, and subsequently enhance ectomesenchyme potential.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

    Jie Wang, Amir Rattner, Jeremy Nathans
    A model of early postnatal bacterial meningitis in the mouse demonstrates the transcriptome responses of each of the major meningeal cell types and should prove useful in dissecting the pathophysiology of bacterial meningitis in human infants.
    1. Neuroscience

    Predominantly linear summation of metabotropic postsynaptic potentials follows coactivation of neurogliaform interneurons

    Attila Ozsvár, Gergely Komlósi ... Gábor Tamás
    Summation of metabotropic GABAergic responses remain linear even if most superficial layer interneurons specialized to recruit GABAB receptors are simultaneously active.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Correlated evolution between repertoire size and song plasticity predicts that sexual selection on song promotes open-ended learning

    Cristina M Robinson, Kate T Snyder, Nicole Creanza
    A longer birdsong-learning window evolves in response to sexual selection for song complexity and is associated with faster evolution of song performance characteristics.