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    1. Neuroscience

    Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers

    Matthias Heindorf, Georg B Keller
    Cell type-specific effects of antipsychotic drugs in cortex could provide a basis for a functional screen of antipsychotic efficacy.
    1. Neuroscience

    Interacting rhythms enhance sensitivity of target detection in a fronto-parietal computational model of visual attention

    Amélie Aussel, Ian C Fiebelkorn ... Benjamin Rafael Pittman-Polletta
    A biophysical cortical circuit model reveals how thalamic inputs mediate complex dynamics in the frontal eye fields and lateral intraparietal area, enabling rhythmic enhancements in visual sensitivity observed behaviorally.
    1. Neuroscience

    Experience shapes chandelier cell function and structure in the visual cortex

    Koen Seignette, Nora Jamann ... Christiaan N Levelt
    Chandelier cells in primary visual cortex show experience-dependent plasticity, respond strongly to behaviorally relevant stimuli and only weakly inhibit pyramidal cells.
    1. Neuroscience

    The locus coeruleus broadcasts prediction errors across the cortex to promote sensorimotor plasticity

    Rebecca Jordan, Georg B Keller
    A brain-wide neuromodulatory system enables rapid cortical plasticity to occur by signaling sensorimotor prediction errors across wide regions of the cerebral cortex.
    1. Neuroscience

    The expression of established cognitive brain states stabilizes with working memory development

    David Florentino Montez, Finnegan J Calabro, Beatriz Luna
    The excessive behavioral variability associated with adolescence is the result of greater instability of widespread or global gain signals which produces greater variability in the amplitude of expression of whole-brain states of task-related activity.
    1. Neuroscience

    Perceptual error based on Bayesian cue combination drives implicit motor adaptation

    Zhaoran Zhang, Huijun Wang ... Kunlin Wei
    Model based on Bayesian cue combination shows that procedural motor learning is driven by perceptual error in localizing one's effector.
    1. Neuroscience

    Parallel visual circuitry in a basal chordate

    Matthew J Kourakis, Cezar Borba ... William C Smith
    The ascidian Ciona integrates visual information from two photoreceptor types through convergent excitatory and disinhibitory circuits, thereby evoking swim behaviors.
    1. Neuroscience

    Human hippocampal CA3 damage disrupts both recent and remote episodic memories

    Thomas D Miller, Trevor T-J Chong ... Clive R Rosenthal
    Human hippocampal cornu ammonis 3 damage impairs both recent and remote autobiographical episodic memory, and disrupts functional integration in medial temporal lobe subsystem regions of the default network.
    1. Neuroscience

    Fundamental processes in sensorimotor learning: Reasoning, refinement, and retrieval

    Jonathan S Tsay, Hyosub E Kim ... Richard B Ivry
    The 3R framework outlines three fundamental processes in motor learning and provides a novel perspective on understanding how we acquire, adapt, and retain complex motor skills.
    1. Neuroscience

    Systematic examination of low-intensity ultrasound parameters on human motor cortex excitability and behavior

    Anton Fomenko, Kai-Hsiang Stanley Chen ... Robert Chen
    Transcranial low-intensity ultrasound applied in block design and at low duty cycles and longer sonication durations can safely and non-invasively suppress human motor-evoked potentials, possibly via GABA-A-mediated inhibitory pathways.