199 results found
    1. Neuroscience

    Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice

    Haneen Kayyal et al.
    aIC to mPFC connections are correlative and necessary both for taste novelty behavior and learning while the reciprocal connection from mPFC to aIC is correlative and necessary for novelty behavior.
    1. Neuroscience

    Human VMPFC encodes early signatures of confidence in perceptual decisions

    Sabina Gherman, Marios G. Philiastides
    Simultaneous EEG-fMRI reveals neural representations of decision confidence unfolding prior to explicit perceptual choices, in a region of the ventromedial prefrontal cortex typically linked to reward processing and value-based decisions.
    1. Neuroscience

    L-DOPA modulates activity in the vmPFC, nucleus accumbens, and VTA during threat extinction learning in humans

    Roland Esser et al.
    Encoding an expected, but absent, threat is modulated by dopaminergic neurotransmission that regulates success of extinction learning in humans.
    1. Neuroscience

    5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex

    Juan Facundo Morici et al.
    Serotonin, a neurotransmitter mostly studied in relation with emotions, also plays an important role in the control of episodic memories.
    1. Neuroscience

    mPFC spindle cycles organize sparse thalamic activation and recently active CA1 cells during non-REM sleep

    Carmen Varela, Matthew A Wilson
    Sleep spindles provide a temporal framework to organize the reactivation of behaviorally relevant CA1 cells and sparsely active cells in the limbic thalamus.
    1. Neuroscience

    How prior preferences determine decision-making frames and biases in the human brain

    Alizée Lopez-Persem et al.
    Model-based analyses of choice behavior and fMRI activity revealed that prior preferences generate default policies, which frame the decision value signal encoded in the vmPFC, and shift vmPFC pre-choice activity so as to induce a decision bias toward default options.
    1. Developmental Biology
    2. Neuroscience

    Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility

    Cassandra B Klune et al.
    An analysis of recent literature advances novel hypotheses and suggests new experimental approaches in order to build an integrated understanding of prefrontal neural architecture and behavioral repertoires during development.
    1. Neuroscience

    The dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other

    Matthew Piva et al.
    Activity in the dorsomedial prefrontal cortex encodes relative subjective value in a common neural code across decision-making for self and other and across tasks with divergent cognitive requirements.
    1. Neuroscience

    Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

    Mingzheng Wu et al.
    Interconnected ventral tegmental area and medial prefrontal cortex circuits causally link dopamine dynamics, aversive learning, and the effects of a promising rapidly acting antidepressant ketamine.
    1. Neuroscience

    Value signals guide abstraction during learning

    Aurelio Cortese et al.
    Valuation of sensory information in the ventromedial prefrontal cortex plays a key function in constructing the abstract representations that guide complex behaviours.

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