102 results found
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Integrating influenza antigenic dynamics with molecular evolution

    Trevor Bedford, Marc A Suchard ... Andrew Rambaut
    Combined antigenic and genetic analysis shows that different strains of the human influenza virus display dramatically different rates of antigenic drift, and that these differences have a significant impact on the number of new infections in each flu season.
    1. Neuroscience

    Homeostatic reinforcement learning for integrating reward collection and physiological stability

    Mehdi Keramati, Boris Gutkin
    A mathematical model built around the assumption that the desire to maintain internal homeostasis drives the behavior of animals, by affecting their learning processes, can explain many real-world behaviors, including some that might otherwise appear irrational.
    1. Computational and Systems Biology
    2. Neuroscience

    Dynamical feature extraction at the sensory periphery guides chemotaxis

    Aljoscha Schulze, Alex Gomez-Marin ... Matthieu Louis
    A computational model for the control of chemotaxis in the Drosophila larva clarifies the link between the peripheral encoding of naturalistic olfactory stimuli and action selection.
    1. Neuroscience

    The neuropeptide tachykinin is essential for pheromone detection in a gustatory neural circuit

    Shruti Shankar, Jia Yi Chua ... Joanne Y Yew
    The cellular and molecular substrates that underlie the programmed behavioral response to a gustatory sex pheromone have been identified.
    1. Neuroscience

    Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions

    Chun-Chieh Lin, Katharine A Prokop-Prigge ... Christopher J Potter
    The activation of Drosophila Or7a receptors guides aggregation and egg-laying behaviors towards both green leaf volatiles and a male-specific food-odor-induced pheromone.
    1. Computational and Systems Biology
    2. Neuroscience

    A cholinergic feedback circuit to regulate striatal population uncertainty and optimize reinforcement learning

    Nicholas T Franklin, Michael J Frank
    Computational modeling suggests that feedback between striatal cholinergic neurons and spiny neurons dynamically adjusts learning rates to optimize behavior in a variable world.
    1. Neuroscience

    Adaptive learning and decision-making under uncertainty by metaplastic synapses guided by a surprise detection system

    Kiyohito Iigaya
    Computational modeling offers an explanation for why animals learn more quickly or slowly when their environment becomes more variable or stable.
    1. Neuroscience

    Unexpected arousal modulates the influence of sensory noise on confidence

    Micah Allen, Darya Frank ... Geraint Rees
    Changes in physiological arousal – as revealed by pupil dilation and heart rate – shape our confidence in decisions about uncertain perceptual information.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Using evolution to generate sustainable malaria control with spatial repellents

    Penelope Anne Lynch, Mike Boots
    The evolution of insecticide-avoidance behaviour can be used to generate new spatial repellents to keep malaria vectors out of homes.
    1. Neuroscience

    The influence of evidence volatility on choice, reaction time and confidence in a perceptual decision

    Ariel Zylberberg, Christopher R Fetsch, Michael N Shadlen
    A single framework of bounded evidence accumulation resolves the seemingly paradoxical effects of noise on accuracy, reaction time and confidence.

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