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    1. Computational and Systems Biology
    2. Neuroscience

    The interpretation of computational model parameters depends on the context

    Maria Katharina Eckstein, Sarah L Master ... Anne GE Collins
    Context factors such as experimental task and model parameterization can significantly impact modeling results, such that across tasks, the same participants show different fitted parameter values, and parameters capture different cognitive processes across tasks.
    1. Genetics and Genomics
    2. Plant Biology

    The genome and phenome of the green alga Chloroidium sp. UTEX 3007 reveal adaptive traits for desert acclimatization

    David R Nelson, Basel Khraiwesh ... Kourosh Salehi-Ashtiani
    Euryhaline green algae utilise intracellular osmoprotectant modulation and specialised redox enzyme networks to successfully inhabit a desert coastline.
    1. Neuroscience

    Control of entropy in neural models of environmental state

    Timothy H Muller, Rogier B Mars ... Jill X O'Reilly
    Evidence for neuromodulatory control of flexibility in human neural models.
    1. Neuroscience

    Neural encoding of task-dependent errors during adaptive learning

    Chang-Hao Kao, Sangil Lee ... Joseph W Kable
    Posterior parietal cortex encodes errors in a task-dependent manner while a large array of frontal regions predict subsequent behavioral changes in response to ambiguous errors.
    1. Cell Biology

    High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast

    Masak Takaine, Hiromi Imamura, Satoshi Yoshida
    The first demonstration that cellular ATP homeostasis suppresses high volatility of cellular ATP levels to ensure proteostasis that prevents accumulation of cytotoxic protein aggregation.
    1. Neuroscience

    Pallidal neuromodulation of the explore/exploit trade-off in decision-making

    Ana Luisa de A Marcelino, Owen Gray ... Tom Gilbertson
    Deep brain stimulation (DBS) exhibit that the excitability of the basal ganglia can govern the trade off between exploiting available resources or exploring alternative courses of action.
    1. Neuroscience

    Humans adapt rationally to approximate estimates of uncertainty

    Erdem Pulcu, Michael Browning
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Offline replay supports planning in human reinforcement learning

    Ida Momennejad, A Ross Otto ... Kenneth A Norman
    fMRI evidence for off-task replay predicts subsequent replanning behavior in humans, suggesting that learning from simulated experience during replay helps update past policies in reinforcement learning.
    1. Neuroscience

    Autistic traits, but not schizotypy, predict increased weighting of sensory information in Bayesian visual integration

    Povilas Karvelis, Aaron R Seitz ... Peggy Seriès
    Autistic traits are associated with weaker influence of prior expectations in visual perception, which is due to more precise sensory representations.