2,136 results found
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response

    Edmée Eyraud, Elise Maurat ... Isabelle Dupin
    Intercellular interactions between fibrocytes and CD8+ T lymphocytes promote inflammation through a pathophysiological positive feedback loop in bronchi of patients with chronic obstructive pulmonary disease (COPD).
    1. Microbiology and Infectious Disease

    Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

    Jennifer A Taylor, Benjamin P Bratton ... Nina R Salama
    The helical bacterium Helicobacter pylori patterns cell wall synthesis using two distinct cytoskeletal proteins, CcmA and MreB, to achieve its characteristic shape.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Functional synergy between the Munc13 C-terminal C1 and C2 domains

    Xiaoxia Liu, Alpay Burak Seven ... Josep Rizo
    Munc13 C-terminal domains synergize to coordinate synaptic vesicle docking, priming and fusion.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Lactoferricins impair the cytosolic membrane of Escherichia coli within a few seconds and accumulate inside the cell

    Enrico F Semeraro, Lisa Marx ... Georg Pabst
    The damage of the bacterial cell envelope is found to be only a secondary effect of the antimicrobial activity of lactoferricin derivatives.
    1. Neuroscience

    Novel cyclic homogeneous oscillation detection method for high accuracy and specific characterization of neural dynamics

    Hohyun Cho, Markus Adamek ... Peter Brunner
    Detecting neural oscillations in time and frequency domains enables the detailed study of spatiotemporal dynamics of oscillations throughout the brain and the investigation of biomarkers that index functional brain areas.
    1. Cell Biology

    Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells

    Jaroslaw Cendrowski, Marta Kaczmarek ... Marta Miaczynska
    Erythroid-enriched BMP2K kinase, in addition to its predicted function in endocytosis, regulates distribution and abundance of COPII assemblies and autophagic degradation through opposing actions of its two splicing variants.
    1. Structural Biology and Molecular Biophysics

    Structural insights into the activation of human calcium-sensing receptor

    Xiaochen Chen, Lu Wang ... Yong Geng
    The cryo-electron microscopy structures of inactive and active states of calcium-sensing receptor (CaSR) reveal the activation mechanisms of CaSR.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes

    Palaniraja Thandapani, Jingwen Song ... Stéphane Richard
    Arginine methylation regulates mRNA translation of key protooncogenes via an RGG/RG motif-containing protein called Aven.
    1. Developmental Biology
    2. Neuroscience

    Cross-modality synthesis of EM time series and live fluorescence imaging

    Anthony Santella, Irina Kolotuev ... Zhirong Bao
    A landmark-based cross-modality alignment method robust to variation in landmark sets is applied to annotate an EM time series of Caenorhabditis elegans embryonic development as a community resource.
    1. Neuroscience

    Coding strategies in the otolith system differ for translational head motion vs. static orientation relative to gravity

    Mohsen Jamali, Jerome Carriot ... Kathleen E Cullen
    Through different coding strategies, irregular and regular otolith afferents preferentially encode translational self-motion and changes in static head orientation relative to gravity.

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