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Class-A penicillin-binding proteins are dispensable for rod-like cell-shape but essential for mechanical integrity by sensing and repairing cell-wall defects locally, as investigated in the model system Escherichia coli.

Mycobacteria employ plasma membrane compartments to organize their cell wall synthesis, and the finalized cell wall compartmentalizes the plasma membrane to promote an environment conducive to its own synthesis.

Dimensionality reduction techniques reveal how the organization of neurotransmitter receptor and transporter co-expression in the human brain may bridge the gap between brain structure and function.

Human brain suggests an asymmetric organization along a functional cortical axis describing a hierarchical functional trajectory from perceptual/action to abstract cognition, which is heritable and comparable with macaque brain, suggesting (phylo)genetic conservation and adaptation.

Major neuron classes are activated when the fly walks, whether it chooses or is forced to do so.

Endocardial Klf2 regulates cardiomyocyte adhesion and myocardial wall integrity by modulating FGF signaling in zebrafish.

Nerve tracing and behavioral studies in tumor-bearing mice together with transcriptional and functional analysis reveal cancer-induced central and peripheral neuronal alterations that influence behavior.

A new computer controlled behavioral assay and integrated training chamber for individual Drosophila larvae shows that larvae learn all at once and create long-term memories that last overnight.

Measuring surface proteins on extracellular vesicles enables quantitative comparison of different isolation methods and optimization of size exclusion chromatography.

Cryo-EM structures reveal how the peptidisc scaffold can adapt to different membrane proteins, establishing it as a universal membrane mimetic to stabilize membrane proteins in solution.