817 results found
    1. Neuroscience

    Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity

    Vincenzo Romano et al.
    Physiological and behavioral analyses show that expression of cerebellar whisker learning can be mediated by increased simple spike activity, depending on LTP induction at parallel fiber to Purkinje cell synapses.
    1. Neuroscience

    Dye-enhanced visualization of rat whiskers for behavioral studies

    Jacopo Rigosa et al.
    A simple fluorescent dye method allows visualization of whiskers, facilitating studies of rodent tactile behavior.
    1. Neuroscience

    Enrichment drives emergence of functional columns and improves sensory coding in the whisker map in L2/3 of mouse S1

    Amy M LeMessurier et al.
    Sensory enrichment creates a more columnar, less salt-and-pepper whisker map in somatosensory cortex, showing that impoverished experience contributes to intermixed tuning in rodent sensory maps.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Regulation of Eag1 gating by its intracellular domains

    Jonathan R Whicher, Roderick MacKinnon
    Interactions between the voltage sensor and intracellular domains modulate voltage-dependent gating and calmodulin inhibition in the voltage-gated potassium channel Eag1.
    1. Neuroscience

    Tapered whiskers are required for active tactile sensation

    Samuel Andrew Hires et al.
    The tapered, conical shape of rodent whiskers is essential for sensor mobility in constrained spaces and feature extraction from textured surfaces.
    1. Neuroscience

    A rapid whisker-based decision underlying skilled locomotion in mice

    Richard A Warren et al.
    A rapid whisker-based decision underlies skilled locomotion in mice largely independent of cerebral cortex.
    1. Neuroscience

    Neural coding in barrel cortex during whisker-guided locomotion

    Nicholas James Sofroniew et al.
    A tactile virtual reality system reveals the neural codes in the barrel cortex that underlie wall-tracking in mice.
    1. Computational and Systems Biology
    2. Developmental Biology

    Modelling the emergence of whisker barrels

    Sebastian S James et al.
    Whisker barrels provide clues about neocortical development, as computer modelling shows that barrels can self-organize, based on competition between adjacent thalamocortical axons, suggesting that genetic instruction plays a secondary role.
    1. Neuroscience

    Peripheral optogenetic stimulation induces whisker movement and sensory perception in head-fixed mice

    Sunmee Park et al.
    Light can be used to trigger the contraction of facial muscles and movement of the whiskers in transgenic mice, aiding the study of active sensation.
    1. Neuroscience

    Coding of whisker motion across the mouse face

    Kyle S Severson et al.
    Electrophysiology and information theory show that diverse classes of mechanoreceptors in the face inform the mouse brain about whisking.

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