1,483 results found
    1. Computational and Systems Biology
    2. Ecology

    Combining agent-based, trait-based and demographic approaches to model coral-community dynamics

    Bruno Sylvain Carturan, Jason Pither ... Lael Parrott
    A new agent-based model enables predicting how coral species richness and functional diversity affect the functioning and resilience of coral reef ecosystems.
    1. Neuroscience

    Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

    Han SJ Cheong, Katharina Eichler ... Gwyneth M Card
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Computational and Systems Biology

    Emergence and propagation of epistasis in metabolic networks

    Sergey Kryazhimskiy
    Mutations that affect a metabolic network generically exhibit epistasis, which propagates to higher level phenotypes, such as fitness, carrying some information about the network’s topology.
    1. Neuroscience

    Uncertainty-based inference of a common cause for body ownership

    Marie Chancel, H Henrik Ehrsson, Wei Ji Ma
    Behavioral and computational results show that the perception of our body as our own depends on Bayesian probabilistic reasoning that take into account the variations in sensory uncertainty when integrating visual and somatosensory cues.
    1. Developmental Biology
    2. Physics of Living Systems

    From local resynchronization to global pattern recovery in the zebrafish segmentation clock

    Koichiro Uriu, Bo-Kai Liao ... Luis G Morelli
    Theory explains how transport of gene expression vortices by cell advection may cause intermingled defective and normal segments along the body axis during resynchronization experiments in the zebrafish segmentation clock.
    1. Microbiology and Infectious Disease

    Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense

    Kelsey Michelle Wells, Kai He ... Paul de Figueiredo
    Brucella facilitates its intracellular parasitism by hijacking the host-regulated IRE1α-dependent decay (RIDD)-BLOS1 innate immune defense system through the disassembly of the BLOC-1-related complex that results in the perinuclear trafficking of Brucella-containing vacuoles and enhanced susceptibility to infection.
    1. Developmental Biology

    The proteolysis of ZP proteins is essential to control cell membrane structure and integrity of developing tracheal tubes in Drosophila

    Leonard Drees, Susi Schneider ... Matthias Behr
    Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.
    1. Computational and Systems Biology
    2. Neuroscience

    Mesoscale cortex-wide neural dynamics predict self-initiated actions in mice several seconds prior to movement

    Catalin Mitelut, Yongxu Zhang ... Timothy H Murphy
    Mouse self-initiated behaviors can be identified seconds prior to action and have similar neuro-dynamical structure to neural dynamics underlying human voluntary actions supporting the use of mouse models in self-initiated and volitional action research.
    1. Neuroscience

    The cellular architecture of memory modules in Drosophila supports stochastic input integration

    Omar A Hafez, Benjamin Escribano ... Jan Pielage
    Computational modeling of a central decision neuron of Drosophila reveals an electrotonically compact architecture that is ideally suited to support efficient memory storage within a stochastically connected memory circuit.

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