1,483 results found
    1. Neuroscience

    Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity

    Vincenzo Romano, Licia De Propris ... Chris I De Zeeuw
    Physiological and behavioral analyses show that expression of cerebellar whisker learning can be mediated by increased simple spike activity, depending on LTP induction at parallel fiber to Purkinje cell synapses.
    1. Neuroscience

    Dye-enhanced visualization of rat whiskers for behavioral studies

    Jacopo Rigosa, Alessandro Lucantonio ... Mathew E Diamond
    A simple fluorescent dye method allows visualization of whiskers, facilitating studies of rodent tactile behavior.
    1. Neuroscience

    Tapered whiskers are required for active tactile sensation

    Samuel Andrew Hires, Lorenz Pammer ... David Golomb
    The tapered, conical shape of rodent whiskers is essential for sensor mobility in constrained spaces and feature extraction from textured surfaces.
    1. Neuroscience

    Enrichment drives emergence of functional columns and improves sensory coding in the whisker map in L2/3 of mouse S1

    Amy M LeMessurier, Keven J Laboy-Juárez ... Daniel E Feldman
    Sensory enrichment creates a more columnar, less salt-and-pepper whisker map in somatosensory cortex, showing that impoverished experience contributes to intermixed tuning in rodent sensory maps.
    1. Neuroscience

    Coding of whisker motion across the mouse face

    Kyle S Severson, Duo Xu ... Daniel H O'Connor
    Electrophysiology and information theory show that diverse classes of mechanoreceptors in the face inform the mouse brain about whisking.
    1. Neuroscience

    Peripheral optogenetic stimulation induces whisker movement and sensory perception in head-fixed mice

    Sunmee Park, Akhil Bandi ... David J Margolis
    Light can be used to trigger the contraction of facial muscles and movement of the whiskers in transgenic mice, aiding the study of active sensation.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Host-selected mutations converging on a global regulator drive an adaptive leap towards symbiosis in bacteria

    M Sabrina Pankey, Randi L Foxall ... Cheryl A Whistler
    Selective forces imposed by the squid animal host drive rapid adaptation of non-native Vibrio fischeri bacteria through convergent mutations of large effect, unmasking preexisting coordinated regulation of symbiosis.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Regulation of Eag1 gating by its intracellular domains

    Jonathan R Whicher, Roderick MacKinnon
    Interactions between the voltage sensor and intracellular domains modulate voltage-dependent gating and calmodulin inhibition in the voltage-gated potassium channel Eag1.
    1. Computational and Systems Biology
    2. Neuroscience

    Decoupling kinematics and mechanics reveals coding properties of trigeminal ganglion neurons in the rat vibrissal system

    Nicholas E Bush, Christopher L Schroeder ... Mitra JZ Hartmann
    Primary sensory neurons of the rat whisker system encode contact with objects in terms of the forces exerted on whiskers, rather than the induced whisker movements.
    1. Neuroscience

    Neural coding in barrel cortex during whisker-guided locomotion

    Nicholas James Sofroniew, Yurii A Vlasov ... Karel Svoboda
    A tactile virtual reality system reveals the neural codes in the barrel cortex that underlie wall-tracking in mice.

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