Cerebellar Purkinje cells represent movements via bidirectional linear changes in spike rate, and activity from single cells is sufficient to reconstruct kinematic changes during bouts of free whisking.
Sebastian S James, Leah A Krubitzer, Stuart P Wilson
Whisker barrels provide clues about neocortical development, as computer modelling shows that barrels can self-organize, based on competition between adjacent thalamocortical axons, suggesting that genetic instruction plays a secondary role.
Primary trigeminal neurons encode rotational forces in awake mice as they explore an object with their whiskers, allowing accurate prediction of spiking during behaviour.
The somatosensory cortex doesn't integrate mixed bilateral inputs, as partially uncrossing projections from the whiskers duplicates their representation by segregating lateralized inputs from each side of the head.
Whole-brain light-sheet imaging of axons segmented by trained convolutional networks reveals distinct projection patterns of genetically defined classes of neurons in primary and secondary whisker-related somatosensory cortices.
Michael R Bale, Malamati Bitzidou ... Miguel Maravall
Mice and humans learned to distinguish an arbitrary tactile sequence from other stimuli that differed only in their temporal patterning over hundreds of milliseconds, showing that sequence learning generalises across sensory modalities.
Magdalena Podkowik, Andrew I Perault ... Bo Shopsin
A new framework for examining tolerance in the context of quorum-sensing that may ultimately help predict and manage bacterial tolerance and, therefore, improve clinical outcome during infection.
