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Normal adipogenesis requires de novo DNA methyltransferase 3A (DNMT3A) for proper differentiation and suppression of an age-associated pathogenic inflammatory program.

A novel transgenic lipid droplet reporter in transparent casper zebrafish allows direct visualization of individual lipid droplets in a living animal.

Inhibiting triglyceride storage in adipose tissue prevents obesity and improves metabolic health.

CD107a expression divides osteogenic from adipogenic perivascular precursor cells within human white adipose tissue.

A combination of cellular, biochemical, genetic and genomic techniques have revealed a new molecular player in the production of fat cells in mice, which could improve our understanding of obesity.

Profiling the adipocyte secretome reveals LRG1 as a novel adipokine that promotes insulin sensitivity and modulates inflammation triggered by release of cytochrome c from dead/dying cells, describing a new pathway at the intersection of obesity and its systemic sequelae.

TAF7L acts as a molecular switch that regulates the development of mesenchymal stem cells.

Reduced energy expenditure in obesity may result from reduced sensitivity to sympathetic activation due to inflammation-generated signals in adipose tissue.

The production of beige adipocytes following cold exposure is blocked as mice get older and leads to changes in the expression of metabolic genes.

ADGRA3 signaling promotes adipose thermogenesis via Gs-PKA-CREB, suggesting hesperetin and ADGRA3 overexpression as obesity therapies.