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    1. Neuroscience

    Differential dopaminergic modulation of spontaneous cortico–subthalamic activity in Parkinson’s disease

    Abhinav Sharma, Diego Vidaurre ... Esther Florin
    Dopaminergic medication has differential effects on the discovered electrophysiological networks, which could be used to develop new electrical and pharmacological interventions in Parkinson’s disease.
    1. Neuroscience

    EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures

    Petteri Stenroos, Isabelle Guillemain ... Emmanuel L Barbier
    Rats with absence epilepsy exhibit hindered and restricted sensory processing during ongoing seizures, as demonstrated by functional magnetic resonance imaging and mean-field simulation studies.
    1. Neuroscience

    Whole-brain mapping of socially isolated zebrafish reveals that lonely fish are not loners

    Hande Tunbak, Mireya Vazquez-Prada ... Elena Dreosti
    Social isolation increases anti-social behaviour by altering activity in brain areas related to anxiety, stress, and reward.
    1. Computational and Systems Biology

    Focal seizures are organized by feedback between neural activity and ion concentration changes

    Damiano Gentiletti, Marco de Curtis ... Piotr Suffczynski
    Biophysically realistic computational model reveals how inhibitory interneurons initiate paroxysmal discharges and how changes in the ionic concentrations shape electrographic features of human seizures.
    1. Neuroscience

    Intrinsic timescales as an organizational principle of neural processing across the whole rhesus macaque brain

    Ana MG Manea, Anna Zilverstand ... Jan Zimmermann
    Neuroimaging proves to be a powerful tool for capturing spatial and temporal dynamics across the whole nonhuman primate brain, bridging the gap between human and animal models.
    1. Computational and Systems Biology
    2. Neuroscience

    Neuroimaging and behavioral evidence that violent video games exert no negative effect on human empathy for pain and emotional reactivity to violence

    Lukas Leopold Lengersdorff, Isabella C Wagner ... Claus Lamm
    After playing violent video games for 7 hr over the course of 2 weeks, human male participants show neither signs of decreased empathy for the pain of another person nor of decreased responsivity to violent images.
    1. Computational and Systems Biology

    The structural connectome constrains fast brain dynamics

    Pierpaolo Sorrentino, Caio Seguin ... Andrew Zalesky
    The fast spreading of neural activity across the brain has a complex structure, imposed by the white-matter bundles.
    1. Neuroscience

    Threat of shock increases excitability and connectivity of the intraparietal sulcus

    Nicholas L Balderston, Elizabeth Hale ... Christian Grillon
    Multimodal neuroimaging was used to study the effect of threat on spontaneous brain activity and functional connectivity, and demonstrated that threat increases both activity and connectivity of the intraparietal sulcus, a key node in the frontoparietal attention network.
    1. Neuroscience

    Whole-brain in situ mapping of neuronal activation in Drosophila during social behaviors and optogenetic stimulation

    Kiichi Watanabe, Hui Chiu, David J Anderson
    While monitoring neuronal activity in freely moving Drosophila is challenging, HI-FISH enables brain-wide mapping of active neurons and reveals behavior-specific neural activity.
    1. Neuroscience

    TMS-evoked responses are driven by recurrent large-scale network dynamics

    Davide Momi, Zheng Wang, John D Griffiths
    Whole-brain computational modelling, incorporating novel ML-based parameter estimation techniques, reveals how transcranial magnetic stimulation-evoked brain responses are driven at earlier timepoints by local echoes of the external stimulus, and at later timepoints by large-scale network reverberation across the connectome.