Crystal structures of Nanos bound to Pumilio and target RNAs demonstrate how Nanos forms a molecular clamp to alter Pumilio RNA regulation and specificity in embryonic development and germline maintenance.

Glucocorticoid receptor directly regulates the transcriptional activity of peroxisome proliferator-activated alpha (PPARα) before birth in anticipation of the sudden shifts in the postnatal nutrient source and metabolic demands.

The discovery of new skeletal remains of Homo naledi in the Lesedi Chamber, South Africa, adds more evidence to our understanding of the morphology and behavior of this recently discovered species.

Subthalamic nucleus spiking activity, beta oscillation power, and locking of spikes to the beta oscillation are decreased prior to changes in ongoing movements.

A theoretical model combines self-supervised predictive learning with structural inductive biases to reveal how quasi-continuous attractors that perform accurate angular path integration can be learned from experience during development in the Drosophila and potentially other animal models.

Neutral tagging and detailed analysis of bacterial growth kinetics can quantify the mechanisms of colonization resistance in differently colonized animals.

A combination of composite-likelihood and gene network-based methods to investigate the impact of Denisovan introgression on the evolution of complex (i.e., polygenic) adaptive traits in high-altitude populations of Tibetan/Sherpa ancestry.

Variably methylated retrotransposons have an underlying sequence that allows them to escape KAP1-mediated silencing and recruit ZF-CxxC proteins.

A close approximation to the successor representation is learnt by a simple spike-time-dependent learning rule between cells undergoing theta phase precession.

Structure–function studies on the synaptic vesicle release protein syntaxin-1 identified structural motifs on the surface of the SNARE complex controlling vesicle priming and spontaneous release unique for synaptic signaling.