Browse the search results

Page 2 of 208
    1. Neuroscience

    TIR-1/SARM1 inhibits axon regeneration and promotes axon degeneration

    Victoria L Czech, Lauren C O'Connor ... Alexandra B Byrne
    TIR-1 regulates both repair and destruction on either side of an injury axon.
    1. Genetics and Genomics

    CLAMP and Zelda function together to promote Drosophila zygotic genome activation

    Jingyue Duan, Leila Rieder ... Erica Larschan
    Maternal CLAMP functions as a novel pioneer transcription factor to open chromatin and plays a targeted yet essential role in Drosophila zygotic genome activation.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

    Alex W Chan, Malgorzata Broncel ... Sebastian Lourido
    Comprehensive characterization of kinase-dependent phosphorylation in the human pathogen Toxoplasma gondii identifies a trafficking adaptor complex required for virulence factor secretion and infection.
    1. Neuroscience

    Asymmetric ON-OFF processing of visual motion cancels variability induced by the structure of natural scenes

    Juyue Chen, Holly B Mandel ... Damon A Clark
    The fruit fly estimates visual motion by incorporating ON-OFF asymmetric processing that only improves performance when stimuli have light-dark asymmetries matched to natural scenes.
    1. Stem Cells and Regenerative Medicine

    Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

    Jacob W Klemm, Chloe Van Hazel, Robin E Harris
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Cell Biology
    2. Evolutionary Biology

    Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

    P Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    OVO positively regulates essential maternal pathways by binding near the transcriptional start sites in the Drosophila female germline

    Leif Benner, Savannah Muron ... Brian Oliver
    Many well-studied maternal developmental pathways that are required for embryonic development in Drosophila are regulated by the transcription factor OVO in the Drosophila female germline.
    1. Cell Biology

    Src activates retrograde membrane traffic through phosphorylation of GBF1

    Joanne Chia, Shyi-Chyi Wang ... Frederic A Bard
    Src phosphorylates GBF1, promoting binding of the Sec7 domain to Arf1 and the formation of GALNTs containing tubules emanating from the Golgi.
    1. Developmental Biology

    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland

    Qiang Lan, Ewelina Trela ... Marja L Mikkola
    Live imaging, transcriptional profiling and mouse models demonstrated that the mesenchyme controls the growth pace but not the mode of branching of the mammary epithelium and unveiled a unique function for Igf1/Igfr1 in embryonic development mammary gland.
    1. Developmental Biology
    2. Genetics and Genomics

    Fat body-specific reduction of CTPS alleviates HFD-induced obesity

    Jingnan Liu, Yuanbing Zhang ... Ji-Long Liu
    Genetic interaction and biochemical analyses have unveiled the crucial involvement of CTPS in the regulation of adipocyte growth, lipid metabolism, and metabolic adaptation in Drosophila, achieved through activating the PI3K-Akt-SREBP pathway.