A novel class of bacterial OTU deubiquitinases provides insights on the distinct roles of bacterial deubiquitinases in host–pathogen interactions.

The voltage-sensing mechanism of a subfamily of potassium channels is modulated in unconventional ways by an amino acid transporter.

Dementia-related tau pathology reduces speed encoding in the medial entorhinal cortex and is associated with reduced grid cell function, whilst head direction tuning remains intact.

The neuronal activity in primary motor cortex does not exhibit smooth low-dimensional dynamics during grasp as it does during reach.

Cryo-EM shows that the NADase activity of SARM1 is allosterically inhibited by physiological concentrations of NAD+ that stabilizes an auto-inhibited conformation of SARM1, explaining how NAD+ depletion may inflict neurodegeneration.

Generation of a human lung single nucleus ATAC-seq and single nucleus RNA-seq datasets reveals candidate cis-regulatory elements that advance knowledge on gene expression control in normal and diseased lungs.

Laminar fMRI reveals that adaptive processing involves recurrent processing within visual cortex and top-down influences from posterior parietal cortex via feedback.

Epithelial cells utilize a covering sheath of motile cells to migrate in confinement.

Mass spectrometry exposes a post-transcriptionally regulated reduction in protein diversity in hematopoietic stem cells, including a lack of detectable Dnmt3a protein levels despite mRNA levels comparable to progenitors.