220 results found
    1. Microbiology and Infectious Disease

    Robust manipulation of the behavior of Drosophila melanogaster by a fungal pathogen in the laboratory

    Carolyn Elya, Tin Ching Lok ... Michael Eisen
    A newly described isolate of the behavior-manipulating fly pathogen Entomophthora muscae that naturally infects fruit flies can be cultured in the lab, enabling molecular investigation of how microbes induce behavior changes in animal hosts.
    1. Physics of Living Systems

    Theory of active self-organization of dense nematic structures in the actin cytoskeleton

    Waleed Mirza, Marco De Corato ... Marino Arroyo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects

    Brian C Ruyle, Sarah Masud ... Jose A Moron
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Developmental Biology
    2. Structural Biology and Molecular Biophysics

    Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

    David R Shook, Eric M Kasprowicz ... Raymond Keller
    Blastopore closure in Xenopus is driven by two morphogenic mechanisms that have strongly context dependent effects on tissue movement and that generate tensile force across tissues: convergent extension, as expected, and, unexpectedly, convergent thickening.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Genetic code expansion, click chemistry, and light-activated PI3K reveal details of membrane protein trafficking downstream of receptor tyrosine kinases

    Duk-Su Koh, Anastasiia Stratiievska ... Sharona E Gordon
    The generation of phosphoinositide 3,4,5-trisphosphate causes an increase in the number of TRPV1 ion channels and insulin receptors in the plasma membrane.
    1. Stem Cells and Regenerative Medicine

    Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling

    Yunyun Jin, Jinjin Xu ... Lei Zhang
    The Brahma chromatin remodelling complex interacts with the Hippo signalling pathway to regulate the proliferation and differentiation of stem cells in the Drosophila midgut.
    1. Cell Biology
    2. Neuroscience

    Activity-dependent mitochondrial ROS signaling regulates recruitment of glutamate receptors to synapses

    Rachel L Doser, Kaz M Knight ... Frederic J Hoerndli
    In response to neuronal activity in vivo, mitochondria in dendrites of excitatory neurons inhibit recruitment of ionotropic glutamate receptors through a reactive oxygen signaling mechanism.
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Vicia faba SV channel VfTPC1 is a hyperexcitable variant of plant vacuole Two Pore Channels

    Jinping Lu, Ingo Dreyer ... Rainer Hedrich
    Polymorphic residues of a vacuolar Ca2+ sensor site in TPC1 channels differ between species of Brassicacea and Fabaceae and lead to distinct TPC1 gating behavior.
    1. Cancer Biology
    2. Immunology and Inflammation

    Preclinical murine tumor models: A structural and functional perspective

    Marion V Guerin, Veronica Finisguerra ... Alain Trautmann
    Dissecting structural, cellular and molecular differences between transplanted and spontaneous mouse tumor models, highlighting their relevance for predicting the efficacy of anti-cancer treatments in patients.
    1. Developmental Biology

    Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient

    Lijuan Du, Alex Sohr ... Sougata Roy
    FGF morphogen gradient self-generates a recipient tissue-specific contour by feedback-regulating its cytoneme-mediated dispersion.

Refine your results by:

Type
Research categories