160 results found
    1. Developmental Biology

    Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network

    Carine Gubelmann et al.
    A large-scale transcription factor screen reveals over twenty novel adipogenic regulators: most notably ZEB1, which exerts essential transcriptional control of fat cell differentiation.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends

    Taylor A Reid et al.
    EB1 targeting to growing microtubule plus-ends is facilitated by tapered microtubule tip structures.
    1. Cell Biology
    2. Developmental Biology

    Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division

    Cuie Chen et al.
    A separation-of-function mutation reveals that a niche ligand receptor Dome functions in spindle orientation during asymmetric stem cell division by directly binding to Eb1, independent of its role in downstream JAK-STAT signaling.
    1. Developmental Biology
    2. Neuroscience

    Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition

    Shalini Singh et al.
    Neuronal progenitor cells autonomously inhibit polarization via the transcription factor Zeb1.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Dissociation rate compensation mechanism for budding yeast pioneer transcription factors

    Benjamin T Donovan et al.
    The budding yeast transcription factors Reb1 and Cbf1 function as pioneer factors by slowly dissociating from nucleosomes, allowing them to target and unwrap nucleosomes efficiently to regulate transcription.
    1. Neuroscience

    Temporal structure in associative retrieval

    Zeb Kurth-Nelson et al.
    Neural representations are fast-evolving trajectories, and distinct components of these trajectories reappear during retrieval with distinct consequences for learning.
    1. Cell Biology

    Lissencephaly-1 is a context-dependent regulator of the human dynein complex

    Janina Baumbach et al.
    An in vitro reconstitution approach reveals context-dependent roles of Lissencephaly-1 in the regulation of dynein-dynactin behaviour on dynamic microtubules.
    1. Cell Biology

    H+- and Na+- elicited rapid changes of the microtubule cytoskeleton in the biflagellated green alga Chlamydomonas

    Yi Liu et al.
    Acidification and salt, which are two major stresses caused by environmental changes, swiftly and drastically alter the microtubule system in green algae and likely many other organisms.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Kinesin-4 KIF21B is a potent microtubule pausing factor

    Wilhelmina E van Riel et al.
    Kinesin-4 KIF21B combines a processive motor activity with two non-motor microtubule-binding domains and an autoregulatory region to induce pausing of microtubule plus ends.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Microtubules: May I check your cap?

    Elisabeth A Geyer et al.
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