Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Neuroscience

    The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

    Lei Li, Guanghao Wu ... Yinchuan Li
    1. Cell Biology
    2. Neuroscience

    Iron-sulfur cluster loss in mitochondrial CISD1 mediates PINK1 loss-of-function phenotypes

    Sara Bitar, Timo Baumann ... Axel Methner
    PINK1 deficiency in Parkinson's disease models causes toxic oxidized and iron-depleted CISD1 yet CISD1 removal benefits PINK1 mutant Drosophila indicating its potential as a therapeutic target for mitochondrial dysfunction and neurodegeneration.
    1. Cell Biology

    Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators

    Roberto Notario Manzano, Thibault Chaze ... Christel Brou
    Proteomic analysis of tunneling nanotubes (TNTs) identifies CD9 and CD81 as major positive regulators of TNT formation.
    1. Cell Biology
    2. Cancer Biology

    RUNX2 Isoform II Protects Cancer Cells from Ferroptosis by Promoting PRDX2 Expression in Oral Squamous Cell Carcinoma

    Junjun Huang, Rong Jia, Jihua Guo
    1. Cell Biology
    2. Neuroscience

    CellSeg3D: self-supervised 3D cell segmentation for microscopy

    Cyril Achard, Timokleia Kousi ... Mackenzie Weygandt Mathis
    1. Cell Biology
    2. Physics of Living Systems

    Hypersensitivity of the vimentin cytoskeleton to net-charge states and Coulomb repulsion

    Bret A Unger, Chun Ying Wu ... Ke Xu
    1. Cell Biology

    Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction

    Ming Zhang, Guangyi Du ... Wei Chen
    Cardiovascular disease, the top cause of diabetic deaths, progresses via vascular endothelial dysfunction, with circHMGCS1 and miR4521 highlighted as potential markers for the development of this condition.
    1. Cell Biology

    Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis

    Davinder Singh, Yajun Liu ... Jian-Qiu Wu
    1. Cell Biology

    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia

    Xiaojiao Hua, Chen Zhao ... Yan Zhou
    1. Cell Biology

    Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

    Raymond Laboy, Marjana Ndoci ... Adam Antebi
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Highlights

    1. Cell Biology

    Burning questions about axons

    Diána Kaszás, Balázs Enyedi
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Cell Biology
    2. Developmental Biology

    Imaging methods are vastly underreported

    Guillermo Marqués, Thomas Pengo, Mark A Sanders

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    The Institute of Photonic Sciences, Spain
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
  4. See more editors