Browse our latest Developmental Biology articles

Page 66 of 210
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Human spinal cord in vitro differentiation pace is initially maintained in heterologous embryonic environments

    Alwyn Dady, Lindsay Davidson ... Kate G Storey
    Comparison of human spinal cord rosette differentiation in vitro and following transplantation into heterologous embryonic environments, reveals cell-intrinsic constraint on human differentiation pace and the importance of timely extrinsic signalling for progression through an intrinsic human neural differentiation programme.
    1. Developmental Biology

    Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair

    Jingqiang Wang, Chunye Liu ... Yi Arial Zeng
    Genetic and mechanistic analyses reveal how ovulatory rupture triggers the activation and expansion of ovarian surface epithelial stem/progenitor cells, through selective activation of Yap, and enhanced expression of Procr by Yap.
    1. Cell Biology
    2. Developmental Biology

    Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish

    Jialing Qi, Annegret Rittershaus ... Christian SM Helker
    Apelin signaling-dependent endocardial protrusions promote cardiac trabeculation through Nrg/ErbB/Erk signaling in zebrafish.
    1. Developmental Biology

    Nephronectin-integrin α8 signaling is required for proper migration of periocular neural crest cells during chick corneal development

    Justin Ma, Lian Bi ... Peter Lwigale
    A new role for nephronectin and integrin α8 signaling during neural crest cell migration in the developing cornea has been identified.
    1. Developmental Biology
    2. Genetics and Genomics

    Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling

    Gang Zhai, Tingting Shu ... Zhan Yin
    Augmentation of progestin signaling promotes testis development and spermatogenesis independent from andorgen signaling in zebrafish.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Paraxial mesoderm organoids model development of human somites

    Christoph Budjan, Shichen Liu ... Sahand Hormoz
    Human somites are formed in organoids from human pluripotent stem cells.
    1. Developmental Biology
    2. Neuroscience

    Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex

    Kawssar Harb, Melanie Richter ... Kent Duncan
    RNA-binding proteins use both translational activation and repression of key molecular determinants to post-mitotically sculpt the identity and connectivity of developing mouse neocortex in an area-specific manner.
    1. Developmental Biology
    2. Evolutionary Biology

    Architecture and evolution of the cis-regulatory system of the echinoderm kirrelL gene

    Jian Ming Khor, Charles A Ettensohn
    The transcriptional control system of a sea urchin gene reveals the deep evolutionary conservation of a gene regulatory network underlying morphogenesis.
    1. Developmental Biology

    Pregnancy: The extraordinary metabolism of vitamin D

    Carol L Wagner, Bruce W Hollis
    The placenta plays an important role in how vitamin D is metabolized and supplied to the fetus.
    Version of Record
    Insight
    1. Developmental Biology

    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit

    Brogan Ashley, Claire Simner ... Jane K Cleal
    Active uptake and metabolism of maternal vitamin D by the placenta determine fetal exposure to vitamin D and how vitamin D regulates the placental transcriptome, which is also determined by its underlying epigenetic landscape, and proteome.