Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Genetics and Genomics

    Determining the effects of paternal obesity on sperm chromatin at histone H3 lysine 4 tri-methylation in relation to the placental transcriptome and cellular composition

    Anne-Sophie Pepin, Patrycja A Jazwiec ... Sarah Kimmins
    Epigenomic and transcriptomic analysis reveals that paternal obesity influences sperm histone H3 lysine 4 tri-methylation enrichment and placenta gene expression, which in turn negatively impact its development and function in a manner that may contribute to metabolic disease in offspring.
    1. Developmental Biology
    2. Neuroscience

    Identification of neurodevelopmental organization of the cell populations of juvenile Huntington’s disease using dorso-ventral HD organoids and HD mouse embryos

    Karolina Świtońska-Kurkowska, Jakub Kubiś ... Maciej Figiel
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Genetics and Genomics

    Gene regulatory dynamics during craniofacial development in a carnivorous marsupial

    Laura E Cook, Charles Y Feigin ... Irene Gallego Romero
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology

    Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

    Emily Delgouffe, Samuel Madureira Silva ... Ellen Goossens
    Gender-affirming hormone therapy in trans women leads to a loss of mature characteristics in the spermatogonial stem cell niche, causes spermatogenic arrest, and triggers fibrotic processes.
    1. Developmental Biology

    An increase in reactive oxygen species underlies neonatal cerebellum repair

    Anna Pakula, Salsabiel El Nagar ... Alexandra L Joyner
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology

    NR2F2 is required in the embryonic testis for Fetal Leydig Cell development

    Aitana Perea-Gomez, Natividad Bellido-Carreras ... Marie-Christine Chaboissier
    Not revised
    Reviewed Preprint v1
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling

    Kara A Nelson, Kari F Lenhart ... Stephen DiNardo
    A new example of niche formation, revealing the mode of niche cell migration, implicates extrinsic sources of positional information, and uncovers the pathway required for stereotypical positioning of the niche.
    1. Computational and Systems Biology
    2. Developmental Biology

    Diversity in Notch ligand-receptor signaling interactions

    Rachael Kuintzle, Leah A Santat, Michael B Elowitz
    The Notch signaling pathway can use its various ligands, receptors, and Fringe proteins to generate diverse intra- and intercellular signaling behaviors.
    1. Developmental Biology

    Reconstruction of functional olfactory sensory tissue from embryonic nasal stem cells

    Kazuya Suzuki, Fumi Wagai, Mototsugu Eiraku
    Not revised
    Reviewed Preprint v1
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Highlights

    1. Developmental Biology

    Patterning the neural plate

    Margaret Hines, Elias Oxman ... Irene Zohn
    1. Developmental Biology

    Signaling pathways in the lung

    Nathaniel C Nelson, Matthias C Kugler
    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer

Senior editors

  1. Utpal Banerjee
    University of California, Los Angeles, United States
  2. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  3. Claude Desplan
    New York University, United States
  4. See more editors