Browse our latest Genetics and Genomics articles

Page 7 of 133
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing

    Jiale Zhou, Ding Zhao ... Zhanjun Li
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Comparative analysis of multiplexed in situ gene expression profiling technologies

    Austin Hartman, Rahul Satija
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Regulatory genome annotation of 33 insect species

    Hasiba Asma, Ellen Tieke ... Marc S. Halfon
    1. Genetics and Genomics

    Post-meiotic mechanism of facultative parthenogenesis in gonochoristic whiptail lizard species

    David V Ho, Duncan Tormey ... Peter Baumann
    Facultative parthenogenesis in whiptail lizards produces genome-wide homozygosity in offspring.
    1. Genetics and Genomics

    Enhancing CRISPR prime editing by reducing misfolded pegRNA interactions

    Weiting Zhang, Karl Petri ... Jing-Ruey Joanna Yeh
    Strategic pegRNA designs and other approaches mitigating 5' and 3' interactions within pegRNAs can often lead to substantial improvements in prime editing efficiency.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase and a cytosine base editor greatly increases transfection and editing rates in Leishmania species

    Nicole Herrmann May, Annika Schmid ... Tom Beneke
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification

    Louna Fruchard, Anamaria Babosan ... Zeynep Baharoglu
    1. Genetics and Genomics
    2. Neuroscience

    Population clustering of structural brain aging and its association with brain development

    Haojing Duan, Runye Shi ... IMAGEN consortium
    1. Cancer Biology
    2. Genetics and Genomics

    DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers

    Jose Mario Bello Pineda, Robert K Bradley
    DUX4 expression is a common feature of metastatic tumors, where it is significantly associated with immune cell exclusion, decreased objective response to immune checkpoint blockade, and reduced patient survival.
    1. Cell Biology
    2. Genetics and Genomics

    Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling

    Jiali Chen, Qinghe Zeng ... Hongting Jin
    Alterations of DNA methylation were associated with articular cartilage degeneration in hemophilic arthropathy, and aberrant methylation and expression of TNXB promote blood-induced chondrocyte apoptosis by regulating AKT activation.
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