Human Biology and Medicine

Human Biology and Medicine

eLife publishes research in clinical and translational research, human genetics, cancer, diabetes and developmental disorders. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Genetics and Genomics
    2. Human Biology and Medicine

    Point of View: Bioengineering horizon scan 2020

    Luke Kemp et al.
    20 emerging issues in bioengineering that will have profound impacts on society have been identified.
    1. Genetics and Genomics
    2. Human Biology and Medicine

    Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell

    Eran Mick et al.
    Mitochondrial electron transport chain dysfunction triggers the integrated stress response due to an asparagine deficiency downstream of impaired NADH oxidation in proliferating myoblasts, but not in differentiated myotubes.
    1. Cell Biology
    2. Human Biology and Medicine

    Activated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2

    Adela Constantinescu-Bercu et al.
    The interaction between activated αIIbβ3 on platelets and SLC44A2 on circulating neutrophils facilitates neutrophil capture and drives flow-dependent NETosis.
    1. Human Biology and Medicine
    2. Immunology and Inflammation

    Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq

    Sara E Vazquez et al.
    Humans with mutations in the AIRE gene exhibit common autoantibodies targeting ovarian and intestinal antigens, including intestinal dysfunction-associated antibodies to enteroendocrine transcription factor RFX6.

Senior editors

  1. Matthias Barton
    University of Zurich, Switzerland
  2. Neil Ferguson
    Imperial College London, United Kingdom
  3. Gary Westbrook
    Vollum Institute, United States
  4. See more editors