Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

    Marisa S Egan, Emily A O'Rourke ... Sunny Shin
    Analysis of inflammasome responses in human macrophages reveals that inflammatory caspases and pyroptotic factors control Salmonella replication primarily within the cytosol and also within vacuoles.
    1. Immunology and Inflammation

    MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

    Linsey JF Peters, Leonida Rakateli ... Emiel PC van der Vorst
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    ImPaqT - A Golden Gate-based Toolkit for Zebrafish Transgenesis

    Saskia Hurst, Christiane Dimmler, Mark R Cronan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5, and MARCHF7

    Li Tian, Zongzheng Zhao ... Zhaolong Li
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice

    Mohsen Khosravi-Maharlooei, Andrea Vecchione ... Megan Sykes
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Thrifty wide-context models of B cell receptor somatic hypermutation

    Kevin Sung, Mackenzie M Johnson ... Frederick A Matsen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Immunology and Inflammation

    Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective

    Douwe Schulte, Marta Šiborová ... Joost Snijder
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Inhibiting NINJ1-dependent plasma membrane rupture protects against inflammasome-induced blood coagulation and inflammation

    Jian Cui, Hua Li ... Congqing Wu
    Procoagulant microvesicles derived from ruptured immune cells fuel blood coagulation.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Neuroscience

    A microglia clonal inflammatory disorder in Alzheimer’s disease

    Rocio Vicario, Stamatina Fragkogianni ... Frédéric Geissmann
    A subset of Alzheimer disease patients carry mutant microglia somatic clones which promote neuro-inflammation.
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