Browse our latest Immunology and Inflammation articles

New tools make it possible to investigate the timing and importance of different immune effectors in defense against infection.

The pathogenic bacteria Shigella avoids detection inside hosts cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.

Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.

The increasing knowledge of barrier tissue-resident memory macrophages and trained innate immunity (TII) will help develop both nontarget-specific and target-specific TII-based vaccine strategies.

scRNA+TCR-seq technology identifies a high proportion of dual TCR Treg cells in both lymphoid and non-lymphoid tissues of mice, revealing their tissue specificity, TCR repertoire characteristics, and functional phenotypes.

The impact of IL10 mutation in birds highlights the intrinsic compromise between effective elimination of a pathogen and damage to the host.

Cell metabolic processes, particularly glucose, glutamine, and lipid metabolism, orchestrate inflammatory responses and promote epigenetic changes shaping microglia immune memory.