Vikrant K Bhosle, Chunxiang Sun ... Lisa A Robinson
SLIT2, a prototypic neuro-repellent, spatiotemporally coordinates host defense against Staphylococcus aureus infection by priming neutrophils and stimulating release of reactive oxygen species and secondary and tertiary granules, potently enhancing bactericidal actions of neutrophils.
Valentin Wernet, Marius Kriegler ... Reinhard Fischer
Fungal hyphae constantly undergo signal oscillations, comparable to a cell 'monologue' until they meet another hypha with which they then coordinate signal oscillations and transit into a cell-to-cell dialogue.
An inducible two-component CRISPR-based platform that rapidly repositions HSV-1 genomes to the nuclear edge unveils intranuclear space heterogeneity for the incoming viral genomes and dynamic stages of the host-virus interplay during early infection.