Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife publishes research covering virology, bacteriology and mycology. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Respiro-Fermentation: To breathe or not to breathe?

    Lauren C Radlinski, Andreas J Bäumler
    Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.
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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Functional and structural segregation of overlapping helices in HIV-1

    Maliheh Safari et al.
    The HIV proteins Env and Rev encode helices that overlap in the viral genome but alternate in functional importance so that the non-functional surface of one helix encodes the functional surface of the other.
    1. Microbiology and Infectious Disease

    Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense

    Kelsey Michelle Wells et al.
    Brucella facilitates its intracellular parasitism by hijacking the host-regulated IRE1α-dependent decay (RIDD)-BLOS1 innate immune defense system through the disassembly of the BLOC-1-related complex that results in the perinuclear trafficking of Brucella-containing vacuoles and enhanced susceptibility to infection.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

    Bretta Hixson et al.
    RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid genome diversification

    Gabriel Machado Matos et al.
    Unique mechanisms of genetic exchange in the important protozoan pathogen Trypanosome cruzi were characterized in detail using genome analyses of hybrid clones at different time points, showing initial tetraploids followed by genome erosion.
    1. Microbiology and Infectious Disease

    Pervasive translation in Mycobacterium tuberculosis

    Carol Smith et al.
    Thousands of novel open-reading frames (ORFs) are translated in the bacterium Mycobacterium tuberculosis, including many short ORFs that are likely to contribute to cell fitness.

Senior editors

  1. Arturo Casadevall
    Johns Hopkins Bloomberg School of Public Health, United States
  2. Miles P Davenport
    University of New South Wales, Australia
  3. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
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