Neuroscience

Neuroscience

eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels

    Carlos AZ Bassetto et al.
    A chain of residues connecting the voltage sensing domain and the pore domain is responsible for a noncanonical communication between these domains.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

    Alicia Tapias et al.
    The Trrap-HAT-Sp1 axis operates a conserved transcriptional program to control proper microtubule dynamics in brain homeostasis and prevents neurodegeneration.
    1. Computational and Systems Biology
    2. Neuroscience

    Sub-minute prediction of brain temperature based on sleep–wake state in the mouse

    Yaniv Sela et al.
    The sleep–wake state sequence explains almost all of the variance in brain temperature in the mouse, and its detailed dynamics can be accurately predicted only using sleep–wake information.
    1. Neuroscience

    Brain endothelial cell TRPA1 channels initiate neurovascular coupling

    Pratish Thakore et al.
    Activation of TRPA1 channels on cerebral capillary endothelial cells initiates a retrograde signal that propagates and dilates upstream arterioles.
    1. Neuroscience

    Incomplete removal of extracellular glutamate controls synaptic transmission and integration at a cerebellar synapse

    Timothy S Balmer et al.
    Extracellular levels of the neurotransmitter glutamate are maintained at physiologically significant levels at some synapses even in the absence of action potentials.

Highlights

    1. Neuroscience

    Decoding the infrastructure of the cerebellum

    Willem S van Hoogstraten, Chris I De Zeeuw

Senior editors

  1. Chris I Baker
    National Institute of Mental Health, National Institutes of Health, United States
  2. Timothy Behrens
    Timothy Behrens
    University of Oxford, United Kingdom
  3. Tirin Moore
    Howard Hughes Medical Institute, Stanford University, United States
  4. See more editors