The water channel AQP4 contributes to a tonic water outflow from brain astrocytes, thereby modulating their volume dynamics and the ambient water homeostasis.
In the CA1 region of the hippocampus, VTA inputs signal reward proximity while LC inputs respond to novelty, illustrating distinct catecholaminergic roles in hippocampal processing during navigation and learning.
Causal investigation of engram ensembles shows that natural forgetting is an active and reversible process driven by perceptual feedback, supporting the perspective of forgetting an adaptive function of the brain.
A global reduction in tRNA differentially affects brain regions and tissues in a mouse model of Polr3-related disease leading to activation of integrated stress and innate immune responses and neurodegeneration.
Quantitative models for responses of rod and cone photoreceptors are developed that allow direct tests of the impact of the photoreceptors on responses of downstream visual neurons.
Sebastian Quiroz Monnens, Casper Peters ... Bernhard Englitz
The recurrent temporal restricted Boltzmann machine applied to whole-brain neuronal recordings from larval zebrafish brains provides substantial advantages in discovering the neuronal assembly structure and their connectivity.
Targeted memory reactivation improved memory performance of easy-to-learn words, but had no effect of difficult-to-learn words, which suggests a critical role of word learning difficulty in sleep associated memory reactivation.
Sex differences in the age-related decline of blood-brain barrier function vary across brain regions, with a more pronounced decrease observed in males beginning in the early 60s.
Allison T Goldstein, Terrence R Stanford, Emilio Salinas
Psychophysical measurements using time pressure indicate that when attention is willfully deployed, a congruent scaccade is automatically planned, but the coupling is weak and can be rapidly broken.
