Browse our latest Neuroscience articles

Peripheral glia regulate synaptic remodeling at the Drosophila neuromuscular junction by balancing neuron-derived signals and controlling ambient glutamate levels, thereby revealing distinct glial mechanisms in activity-dependent synaptic plasticity.

PTBP1 loss in mature astrocytes causes unique astrocytic splicing changes, not neuronal-like, contrasting its role in other non-neuronal cells and indicating PTBP1 depletion alone is ineffective to drive adult-astrocyte-to-neuron conversion.

Remote memories in Alzheimer’s disease are impaired through loss of inhibitory control over cortical engram neurons by hyperexcitable parvalbumin interneurons.

Patch-seq RNA profiling defines the overall RNA editing landscape and single neuron editing rules for individual genetically defined Drosophila larval motoneurons.

Cholecystokinin gates age-dependent auditory thalamocortical plasticity and, upon supplementation, reverses age-related plasticity decline and improves frequency discrimination.

The review proposes a novel mechanistic distinction between first- and second-order traveling waves that subserves a same canonical computation by ordering neuronal processing to impose a computational syntax.

Sensitive brain activity mapping and behavioral profiling reveal most microexons are dispensable for early brain development but highlight a small subset with intriguing neural phenotypes for future study.