The spiking activity of the subthalamic nucleus, rather than the activity of striatal projection neurons, orchestrates basal ganglia downstream activity and output commands in health and Parkinson’s disease.
Janelle MP Pakan, Scott C Lowe ... Nathalie L Rochefort
The three main types of inhibitory neurons in mouse primary visual cortex respond differently to locomotion in darkness and during visual stimulation, revealing context-dependent responses to changes in behavioral state.
Onno D Broekmans, Jarlath B Rodgers ... Greg J Stephens
A conceptually simple algorithm can analyze previously uncharacterized 2D coiled postures of the nematode C. elegans and has uncovered new reorientation behaviors in large amplitude turns.
Joanna M Dragich, Takaaki Kuwajima ... Ai Yamamoto
Loss of function of the selective autophagy adaptor protein Alfy/Wdfy3 leads to profound wiring defects from the forebrain through to the spinal cord, highlighting the growing importance for macroautophagy in the developing brain.
Neural networks like the crustacean cardiac ganglion employ multi-faceted compensatory mechanisms to achieve the stability and robustness that are critical to long-term function.