Empirical evidence suggests that the hippocampus constructs maps of spatial environments based on the relative locations of places (i.e., topology), rather than absolute distances and coordinates (i.e., geometry).
Farzaneh Najafi, Andrea Giovannucci ... Javier F Medina
Sensory-driven calcium spikes in Purkinje cells are not binary; instead, they are graded and can provide information about the strength of a periocular airpuff stimulus known to drive learning.
A protein within the nuclear membrane, MAN1, controls the expression of the circadian clock gene, BMAL1, in an example of cross-talk between two major gene regulatory pathways.
A non-coding RNA-based targeting mechanism could potentially epigenetically maintain specialized chromatin structures, such as the centromere, in vivo.
Megumi Hatori, Shubhroz Gill ... Satchidananda Panda
A transcription factor called Lhx1 coordinates the activity of the brain's master circadian clock, the suprachiasmatic nucleus, by controlling communication between its constituent cells.
Katrin Vogt, Christopher Schnaitmann ... Hiromu Tanimoto
One memory center in the fly brain processes distinct appetitive and aversive associative memories of olfactory and visual cues using shared local circuits.
